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Related Concept Videos

Inflammatory Bowel Disease V: Surgical Management01:21

Inflammatory Bowel Disease V: Surgical Management

Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:

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Related Experiment Video

Updated: Jun 18, 2026

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications
09:41

Surgical Closure of Equine Abdomen, Prevention, and Management of Incisional Complications

Published on: May 10, 2024

Failed exstrophy closure: management and outcome.

Thomas E Novak1, John P Costello, Ryan Orosco

  • 1Division of Pediatric Urology, James Buchanan Brady Urological Institutions, Johns Hopkins Hospital, Johns Hopkins Medical Institutions, Marburg 149, 600 North Wolfe Street, Baltimore, MD 21287, USA. thomas.novak@amedd.army.mil

Journal of Pediatric Urology
|November 13, 2009
PubMed
Summary
This summary is machine-generated.

Repeat closure for bladder exstrophy is highly successful, but achieving urethral continence is more challenging than after primary closure. Many patients require clean intermittent catheterization or continent urinary diversion for dryness.

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Last Updated: Jun 18, 2026

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A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing
20:33

A Case Series of Successful Abdominal Closure Utilizing a Novel Technique Combining a Mechanical Closure System with a Biologic Xenograft that Accelerates Wound Healing

Published on: July 4, 2019

Area of Science:

  • Pediatric Urology
  • Reconstructive Surgery

Background:

  • Bladder exstrophy closure failures present complex reconstructive challenges.
  • Understanding factors influencing repeat closure success is crucial for patient outcomes.

Purpose of the Study:

  • To identify determinants of successful repeat bladder exstrophy closure.
  • To assess the impact of failed closures on lower urinary tract function and continence.

Main Methods:

  • Retrospective review of 122 patients with prior failed exstrophy closures (1978-2007).
  • Analysis of repeat closure success rates, continence surgery, and continence outcomes.
  • Continence defined as >3h dry interval and urethral voiding.

Main Results:

  • Repeat closure success rate was 98% at the institution.
  • Of 94 successfully reclosed patients evaluated, 18% achieved urethral continence.
  • 90% achieved dryness via clean intermittent catheterization or continent urinary diversion.

Conclusions:

  • Failed bladder exstrophy closure significantly impacts long-term surgical results.
  • Repeat closure is feasible in most cases.
  • Urethral continence rates are lower after successful repeat closure compared to primary closure.