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Published on: April 1, 2022
When harvested for coronary artery bypass graft surgery, does a skeletonized or pedicled radial artery improve
Erden Ali1, Srdjan Saso, Kamran Ahmed
1Department of Biosurgery-Surgical Technology and Surgical Epidemiology Unit, Imperial College London, 10th Floor, QEQM building, Imperial College Healthcare NHS Trust at St Mary's Hospital, Praed Street, London W2 1NY, UK.
Insights
Skeletonization of the radial artery (RA) in coronary artery bypass grafting (CABG) shows excellent short- and medium-term patency rates. Comparative studies suggest skeletonized RA conduits may offer superior patency compared to pedicled techniques.
Area of Science:
- Cardiac Surgery
- Vascular Grafting
Background:
- Coronary artery bypass grafting (CABG) is a common surgical procedure.
- Radial artery (RA) is a frequently used conduit in CABG.
- The technique of conduit preparation, skeletonization versus pedicling, may influence graft patency.
Purpose of the Study:
- To evaluate the evidence regarding whether skeletonization of the radial artery (RA) improves conduit patency in coronary artery bypass grafting (CABG).
Main Methods:
- A structured literature search identified 15 relevant papers.
- Four papers were selected as the best evidence.
- Two comparative studies assessed patency rates between skeletonized and pedicled RA conduits.
Main Results:
- Short- and medium-term patency rates for skeletonized RA conduits are excellent, exceeding 95% in all reviewed studies.
- In comparative studies, skeletonized RA conduits demonstrated superior patency compared to pedicled conduits.
- Patency rates reported were 100% within 18 days, 98.3% at 3 months, and 97.6% at 1 year.
Conclusions:
- Skeletonization of the radial artery (RA) in CABG is associated with excellent short- and medium-term patency.
- Evidence suggests that skeletonization may provide a patency benefit over the pedicled technique for RA conduits.
- Further research is needed to assess long-term patency beyond 5 years.
Abstract:
A best evidence topic in cardiac surgery was written according to a structured protocol. The question addressed was whether skeletonization of the radial artery (RA) improves conduit patency in coronary artery bypass grafting (CABG). Altogether 15 papers were found using the reported search, of which four papers represented the best evidence to answer the clinical question. Two papers compared patency rates between skeletonized and pedicled radial arteries. The author, journal, date and country of publication, patient group studied, study type, relevant outcomes and results are tabulated. We acknowledge that evidence is limited in this area of cardiac surgery. When assessing the skeletonized RA, three studies provided patency data one year after CABG. No patency data were available five years after CABG. Only two papers were comparative studies (skeletonized conduits vs. pedicled conduits). Despite the above, short- and medium-term patency rates of skeletonized conduits are excellent. In the two comparative studies, patency of skeletonized vessels was superior to the pedicled conduits. Patency was assessed with the use of angiography and rates exceeded 95% in all four studies. Overall patency rates were 100% within 18 days, 98.3% within three months, 97.6% at a mean of approximately 1 year, and 100% at 4 years in one study. From these studies, we can conclude that the patency rates of pedicled conduits are excellent, however, our study suggests that skeletonization may offer the radial conduit some patency benefit when compared to the pedicled technique. The remaining two non-comparative studies support the above conclusion.
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