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Non-Rotavirus infection causing apnea in a neonate
Majeeda Kamaluddeen1, Abhay Lodha, Albert Akierman
1Department of Pediatrics, University of Calgary & Peter Lougheed Hospital, AB, Canada. Majeeda.Kamaluddeen@CalgaryHealthRegion.ca
Indian Journal of Pediatrics
|November 13, 2009
Summary
Apnea in premature infants may have non-immaturity causes. A case study found Norovirus infection triggered apnea unresponsive to caffeine, resolving with conservative care.
Area of Science:
- Neonatal Medicine
- Pediatric Gastroenterology
- Infectious Diseases
Background:
- Apnea of prematurity is commonly treated with caffeine.
- Non-immaturity related causes of apnea in preterm infants require consideration.
Observation:
- A preterm infant presented with increasing apnea frequency at two weeks of life.
- The infant's apnea was refractory to caffeine treatment.
- A sibling had a history of diarrhea, prompting further investigation.
Findings:
- Stool PCR confirmed Norovirus Genogroup II infection.
- Enteric isolation was implemented for the infant.
- Apnea resolved spontaneously with conservative management after isolation.
Implications:
- Norovirus infection should be considered in preterm infants with refractory apnea.
- This case highlights the importance of investigating non-immaturity related etiologies for apnea.
- Early identification and isolation can aid in managing infectious causes of apnea in neonates.
