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Acanthameba meningitis with successful outcome.

Ajit Saxena¹, Sumit Mittal, Purbi Burman

¹Department of Pediatrics and Microbiology, Fortis Hospital, Sita Ram Bhartia Institute of Science and Research, New Delhi, India.

Indian Journal of Pediatrics

|November 13, 2009

Summary

A rare case of subacute meningitis caused by Acanthamoeba in an immunocompetent child was successfully treated. The 9-month treatment regimen included Ketoconazole, Rifampicin, and Cotrimoxazole.

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Area of Science:

Neurology
Infectious Diseases
Microbiology

Background:

Subacute meningitis can have diverse etiologies.
Acanthamoeba infections are rare, particularly in immunocompetent individuals.

Observation:

A 15-year-old immunocompetent female presented with subacute meningitis.
The causative agent was identified as Acanthamoeba.

Findings:

Successful treatment of Acanthamoeba meningitis was achieved.
A combination therapy including Ketoconazole, Rifampicin, and Cotrimoxazole was administered for nine months.

Implications:

This case highlights Acanthamoeba as a potential cause of meningitis in immunocompetent hosts.
Effective treatment strategies for rare Acanthamoeba infections can be developed.
Further research into Acanthamoeba meningitis in pediatric populations is warranted.