Related Experiment Video
Updated: Jun 18, 2026

Multiomics Analysis of TMEM200A as a Pan-Cancer Biomarker
Published on: September 15, 2023
Advances in thymosin beta10 research: differential expression, molecular mechanisms, and clinical implications in
Sirinapa Sribenja1, Min Li, Sopit Wongkham
1Molecular Surgeon Research Center, Division of Vascular Surgery and Endovascular Therapy, Michael E. DeBakey Department of Surgery, Baylor College of Medicine, Houston, Texas, USA.
Abstract:
Thymosin beta 10 (Tbeta10) is a member of the beta-thymosin family, which has biological activities as an actin-sequestering protein involved in cell motility. Tbeta10 may be correlated with tumor biology such as cell proliferation, apoptosis, angiogenesis, and metastasis behavior. However, the molecular mechanisms of action of Tbeta10 in cancer are largely unknown. Tbeta10 is differentially expressed in embryogenesis and neuronal development. Its expression is also increased in many inflammatory conditions and tumorigenesis. This review briefly summarizes recent advances in Tbeta10 research including differential expression, functions, mechanisms, gene regulation, and therapeutic applications in cancer, wound healing, and other diseases.
Related Concept Videos
Pharmacogenetics of Drug Targets: β₂-Adrenergic Receptors, Apo E, Thymidylate Synthase
Targeted Cancer Therapies
There are several types of targeted therapies against specific...
Tumor Immunotherapy
TGF - β Signaling Pathway
Cancer Therapies
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
