Laparoendoscopic single-site and conventional laparoscopic adrenalectomy: a matched case-control study

Area of Science:

• Minimally Invasive Surgery
• Surgical Oncology
• Urology

Background:

• Benign adrenal adenomas are common endocrine tumors.
• Conventional laparoscopic adrenalectomy is a standard treatment.
• Advancements in surgical techniques aim to improve patient outcomes and cosmesis.

Purpose of the Study:

• To evaluate the initial clinical experience with laparoendoscopic single-site surgery (LESS) for benign adrenal adenoma.
• To assess the feasibility and safety of LESS adrenalectomy.
• To compare LESS with conventional laparoscopic adrenalectomy.

Main Methods:

• A retrospective comparison of 9 patients undergoing LESS adrenalectomy with 17 patients undergoing conventional laparoscopic adrenalectomy.
• Patients were matched for age, sex, indications, and tumor size.
• Outcomes analyzed included operative time, blood loss, postoperative hospital stay, pain, and complications.

Main Results:

• No significant differences were found in operative time, blood loss, or hospital stay between LESS and conventional laparoscopy.
• Postoperative pain, measured by IV patient-controlled anesthesia use, was significantly lower in the LESS group (0.9 vs. 1.9 days, p = 0.047).
• Perioperative complication rates were similar between the two groups.

Conclusions:

• LESS adrenalectomy is a feasible and comparable alternative to conventional laparoscopy for benign adrenal adenoma.
• LESS offers potential benefits in terms of reduced postoperative pain and improved cosmetic outcomes.
• Further research may explore wider adoption of LESS for adrenal pathologies.