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Updated: Jun 18, 2026

Localization, Identification, and Excision of Murine Adipose Depots
Published on: December 4, 2014
Is the way to man's heart (and lung) through the abdomen?
Robert L Owens1, R Scott Harris, Atul Malhotra
1Sleep Disorders Research Program, Division of Sleep Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, MA 02115, USA. rowens@partners.org
Abstract:
Intra-abdominal hypertension is increasingly recognized to be both prevalent and clinically important in medical and surgical intensive care units. Intra-abdominal pressure (IAP) can impact organ function throughout the body, and it can also complicate standard measurements used in intensive care units. The article by Krebs and colleagues reports the effect of IAP on respiratory function, gas exchange and hemodynamic function. Their results show a relatively small effect of modestly elevated IAP on these variables in their patient population. However, their work raises several questions for clinicians and researchers regarding the pathophysiology and management of IAP.
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