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A new cytotoxic flavonoid from the fruit of Sinopodophyllum hexandrum
Yue Kong1, Jun-Jun Xiao, Shu-Cong Meng
1Department of Natural Medicines, School of Pharmaceutical Sciences, Peking University, Beijing, China.
Fitoterapia
|November 14, 2009
Abstract:
Constituents of the fruit of Sinopodophyllum hexandrum (Royle) Ying (Sinopodophylli Fructus) were investigated. A new flavonoid, 8,2'-diprenylquercetin 3-methyl ether along with 9 known compounds were isolated and identified. Among them, the new compound 8,2'-diprenylquercetin 3-methyl ether exhibited cytotoxic activities against MDA-231 and T47D breast cancer cell lines, quercetin, kaempferol and rutin were isolated from Sinopodophylli Fructus for the first time.
