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Related Experiment Video

Updated: Jun 18, 2026

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
08:00

Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter

Published on: June 15, 2015

Optimal branch selection in alcohol septal ablation.

Konstantinos Toutouzas, Antonis Karanasos, Aris Anastasakis

    International Journal of Cardiology
    |November 14, 2009
    PubMed
    Summary

    Alcohol septal ablation effectively reduces the subaortic gradient in hypertrophic obstructive cardiomyopathy. Myocardial contrast echocardiography aids in selecting the optimal septal branch for this procedure, improving patient outcomes.

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    Area of Science:

    • Cardiology
    • Interventional Cardiology
    • Cardiac Imaging

    Background:

    • Hypertrophic obstructive cardiomyopathy (HOCM) presents challenges in managing the subaortic gradient.
    • Alcohol septal ablation is an evolving interventional technique for HOCM treatment.
    • Precise localization of septal branches is crucial for successful ablation.

    Observation:

    • Myocardial contrast echocardiography (MCE) is utilized to identify the perfusion territory of individual septal branches.
    • A case study involving a 78-year-old woman with HOCM is presented.
    • Echocardiographic and angiographic data guided the selection of the target septal branch.

    Findings:

    • Alcohol septal ablation was successfully performed without immediate complications.
    • The procedure led to a significant reduction in the subaortic gradient.

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    Last Updated: Jun 18, 2026

    Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter
    08:00

    Reduction of Iatrogenic Atrial Septal Defects with an Anterior and Inferior Transseptal Puncture Site when Operating the Cryoballoon Ablation Catheter

    Published on: June 15, 2015

    Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing
    12:45

    Benefits of Cardiac Resynchronization Therapy in an Asynchronous Heart Failure Model Induced by Left Bundle Branch Ablation and Rapid Pacing

    Published on: December 11, 2017

    Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation
    28:13

    Catheter Ablation in Combination With Left Atrial Appendage Closure for Atrial Fibrillation

    Published on: February 26, 2013

  • The patient experienced an improvement in functional capacity post-ablation.

    • Implications:

    • MCE is a valuable tool for optimizing septal branch selection in alcohol septal ablation.
    • This technique offers a viable treatment option for HOCM patients with obstructive subaortic gradients.
    • Further research may solidify MCE's role in interventional cardiology for HOCM.