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Updated: Jun 18, 2026
07:42
An Image Guided Transapical Mitral Valve Leaflet Puncture Model of Controlled Volume Overload from Mitral Regurgitation in the Rat
Published on: May 19, 2020
Transient severe reversible functional mitral regurgitation: a three-dimensional transoesophageal perspective
Vincent Labbe1, Patrick Charlier, Eric Brochet
1Cardiology Department, AP-HP, Bichat Hospital, 46 rue Henri Huchard, 75018 Paris, France.
Summary
Severe mitral regurgitation can be reversible and functional, not always organic. Advanced imaging like transesophageal echocardiography revealed temporary leaflet issues causing this condition.
Area of Science:
- Cardiology
- Medical Imaging
- Cardiac Physiology
Background:
- Mitral regurgitation (MR) is a significant valvular heart disease.
- Distinguishing between organic and functional MR is crucial for treatment.
- Patient presented with symptoms suggestive of severe MR.
Observation:
- Initial transthoracic echocardiography indicated moderate organic MR.
- Transesophageal echocardiography (TEE) revealed transient, severe, reversible functional MR.
- Three-dimensional TEE provided detailed visualization of the mitral valve dynamics.
Findings:
- Functional MR was characterized by sudden, transient leaflet tenting.
- A circular mitral annulus was observed during the regurgitant phase.
- Complete absence of leaflet coaptation led to severe regurgitation.
Implications:
- Highlights the importance of dynamic imaging in MR assessment.
- Suggests potential for non-surgical management in reversible functional MR.
- Emphasizes the role of advanced echocardiography in diagnosing complex valvular pathologies.
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