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Updated: Jun 18, 2026

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies
06:38

A Syngeneic Mouse Model of Metastatic Renal Cell Carcinoma for Quantitative and Longitudinal Assessment of Preclinical Therapies

Published on: April 12, 2017

Successful treatment of a brain-metastasized renal cell carcinoma

M Sami Walid1, Kim W Johnston

  • 1Medical Center of Central Georgia, Macon, GA, USA. mswalid@yahoo.com

German Medical Science : GMS E-Journal
|November 14, 2009
PubMed

Insights

Renal cell carcinoma rarely spreads to the brain, with a poor prognosis. This case highlights successful multimodal treatment for brain metastases from renal cell carcinoma using novel medication.

Area of Science:

  • Oncology
  • Neurology
  • Nephrology

Background:

  • Renal cell carcinoma (RCC) is a rare cancer.
  • Brain metastasis from RCC is uncommon and associated with poor outcomes.

Observation:

  • A patient presented with multiple brain metastases secondary to renal cell carcinoma.
  • The patient's prognosis was historically considered poor due to the brain involvement.

Findings:

  • The patient received successful multimodal therapy.
  • Treatment included a novel therapeutic agent, leading to positive outcomes.

Implications:

  • This case suggests that multimodal therapy, including new medications, can improve outcomes for RCC with brain metastasis.
  • Further research into novel treatments for rare metastatic presentations of RCC is warranted.
Keywords:
brain metastasisrenal cell carcinomasorafenib

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