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Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
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Mycoses in the elderly

H Hof1

  • 1Labor Limbach, Heidelberg, Germany. hyg-mannheim@gmx.de

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|November 14, 2009
PubMed

Insights

Fungal infections like dermatophytosis are common in older adults, influenced by health conditions and circulation. Early diagnosis and prevention are key for managing these infections in the elderly.

Area of Science:

  • Mycology
  • Geriatrics
  • Infectious Diseases

Background:

  • Fungal infections, particularly dermatophytosis, are more common in the elderly.
  • Risk factors include local trophic disturbances, diabetes, and poor circulation.
  • Systemic yeast infections and specific fungal pathogens like Candida glabrata and Coccidioides immitis are notable in this age group.

Purpose of the Study:

  • To review the prevalence and characteristics of fungal infections in the elderly.
  • To identify risk factors and challenges in diagnosing and treating these infections in older adults.
  • To highlight the importance of preventive measures for fungal infections in geriatric populations.

Main Methods:

  • Literature review of fungal infections in the elderly.
  • Analysis of risk factors, clinical manifestations, and diagnostic challenges.
  • Discussion of therapeutic implications and preventive strategies.

Main Results:

  • Dermatophyte infections are prevalent in the elderly, with increased risk from comorbidities and circulatory issues.
  • Vaginal mycoses are rare, but Candida glabrata is significant in systemic yeast infections.
  • Coccidioides immitis prevalence increases in endemic areas among the elderly.
  • Infections may present atypically in older adults, complicating diagnosis.
  • Organ function deficits can impact antifungal drug efficacy.

Conclusions:

  • Fungal infections in the elderly present unique challenges due to altered physiology and comorbidities.
  • Preventive strategies focusing on social environment, nutrition, immunosenescence, and hygiene are crucial.
  • Tailored diagnostic and therapeutic approaches are necessary for effective management of fungal infections in geriatric patients.

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