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Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis
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Bio-energetics Investigation of Candida albicans Using Real-time Extracellular Flux Analysis

Published on: March 19, 2019

Mycoses in the elderly.

H Hof1

  • 1Labor Limbach, Heidelberg, Germany. hyg-mannheim@gmx.de

European Journal of Clinical Microbiology & Infectious Diseases : Official Publication of the European Society of Clinical Microbiology
|November 14, 2009
PubMed
Summary
This summary is machine-generated.

Fungal infections like dermatophytosis are common in older adults, influenced by health conditions and circulation. Early diagnosis and prevention are key for managing these infections in the elderly.

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Area of Science:

  • Mycology
  • Geriatrics
  • Infectious Diseases

Background:

  • Fungal infections, particularly dermatophytosis, are more common in the elderly.
  • Risk factors include local trophic disturbances, diabetes, and poor circulation.
  • Systemic yeast infections and specific fungal pathogens like Candida glabrata and Coccidioides immitis are notable in this age group.

Purpose of the Study:

  • To review the prevalence and characteristics of fungal infections in the elderly.
  • To identify risk factors and challenges in diagnosing and treating these infections in older adults.
  • To highlight the importance of preventive measures for fungal infections in geriatric populations.

Main Methods:

  • Literature review of fungal infections in the elderly.
  • Analysis of risk factors, clinical manifestations, and diagnostic challenges.
  • Discussion of therapeutic implications and preventive strategies.

Main Results:

  • Dermatophyte infections are prevalent in the elderly, with increased risk from comorbidities and circulatory issues.
  • Vaginal mycoses are rare, but Candida glabrata is significant in systemic yeast infections.
  • Coccidioides immitis prevalence increases in endemic areas among the elderly.
  • Infections may present atypically in older adults, complicating diagnosis.
  • Organ function deficits can impact antifungal drug efficacy.

Conclusions:

  • Fungal infections in the elderly present unique challenges due to altered physiology and comorbidities.
  • Preventive strategies focusing on social environment, nutrition, immunosenescence, and hygiene are crucial.
  • Tailored diagnostic and therapeutic approaches are necessary for effective management of fungal infections in geriatric patients.