Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Stem Cell Therapy for Tissue Regeneration01:21

Stem Cell Therapy for Tissue Regeneration

Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell types that...
Stem Cell Culture01:17

Stem Cell Culture

Stem cell research aims to find ways to use stem cells to regenerate and repair cellular damage. Over time, most adult cells undergo the wear and tear of aging and lose their ability to divide and repair themselves. Stem cells do not display a particular morphology or function. Adult stem cells, which exist as a small subset of cells in most tissues, keep dividing and can differentiate into a number of specialized cells generally formed by that tissue. These cells enable the body to renew and...
Adult Stem Cells01:33

Adult Stem Cells

Stem cells are undifferentiated cells that divide and produce more stem cells or progenitor cells that differentiate into mature, specialized cell types. All the cells in the body are generated from stem cells in the early embryo, but small populations of stem cells are also present in many adult tissues including the bone marrow, brain, skin, and gut. These adult stem cells typically produce the various cell types found in that tissue—to replace cells that are damaged or to continuously renew...
Embryonic Stem Cells00:58

Embryonic Stem Cells

Embryonic stem (ES) cells are undifferentiated pluripotent cells, meaning they can produce any cell type in the body. This gives them tremendous potential in science and medicine since they can generate specific cell types for use in research or to replace body cells lost due to damage or disease.
Embryonic Stem Cells00:57

Embryonic Stem Cells

Embryonic stem (ES) cells were first discovered in mice in 1981 by Martin Evans. In 1998, James Thomson identified a method to isolate embryonic stem cells from humans. Human embryonic stem cells (hESCs) are obtained from 3-5 day old embryos that remain unused after an in vitro fertilization procedure.
ES cells are grown in a culture medium where they can divide indefinitely, creating ES cell lines. Under certain conditions, ES cells can differentiate, either spontaneously into a variety of...
Source And Potency Of Stem Cells01:27

Source And Potency Of Stem Cells

Stem cells are undifferentiated cells with extensive self-renewal properties that help them maintain their population during the fetal and adult stages of life. They can specialize in all cell types of the human body. However, their differential potential may vary and can be classified into five types. Stem cells can be (1) Totipotent, (2) Pluripotent, (3) Multipotent, (4) Oligopotent, and (5) Unipotent. Each stem cell has a specific origin; the fertilized egg or zygote is a totipotent cell and...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Closing the epidemiologic gap in keloid disease: A call to action for investigative dermatology.

The Journal of investigative dermatology·2026
Same author

The In Vitro Wound-Scratch Assay: Applications, Technical Advances, and Limitations in Wound Healing Research.

International wound journal·2026
Same author

Decoding keloids: Single-cell heterogeneity, emerging role of adipocytes, molecular biomarkers, and therapeutic implications in skin of color.

The Journal of investigative dermatology·2026
Same author

Survival study of cytoreductive prostatectomy for prostate cancer with lung metastasis: A propensity score matching study based on the SEER database.

PloS one·2026
Same author

Corrigendum to 'Superior Antiproliferative and Enhanced Synergistic Effects of a Rock Inhibitor in Multiple Models for Keloid Disease' JID Innovations, Volume 5, Issue 6, November 2025, 100402.

JID innovations : skin science from molecules to population health·2026
Same author

Advances in Silicone Implants Characterization: A Comprehensive Overview of Chemical, Physical and Biological Methods for Biocompatibility Assessment.

Bioengineering (Basel, Switzerland)·2025
Same journal

Hearing aids in low- and middle-income countries: from evidence to scale.

Expert review of medical devices·2026
Same journal

Point-of-care ultrasound in cardiovascular imaging: current status and future prospects.

Expert review of medical devices·2026
Same journal

Challenges associated with device therapy for pediatric patients with sleep apnea.

Expert review of medical devices·2026
Same journal

Review of regulatory requirements for benefit - risk assessment for medical devices: uncovering existing methodologies.

Expert review of medical devices·2026
Same journal

Two sides to every wrist: trans-ulnar access for cardiac interventions.

Expert review of medical devices·2026
Same journal

Comparative review of coronary CT angiography versus conventional catheter angiography: diagnostic value, clinical outcomes, and underlying technical principles.

Expert review of medical devices·2026
See all related articles

Related Experiment Video

Updated: Jun 18, 2026

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
13:04

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model

Published on: March 18, 2015

Adult stem cells in tissue engineering.

Thomas Hodgkinson1, Xue-Feng Yuan, Ardeshir Bayat

  • 1Plastic and Reconstructive Surgery Research, and School of Chemical Engineering and Analytical Science, Manchester Interdisciplinary Biocentre, 131 Princess Street, University of Manchester, Manchester M17DN, UK.

Expert Review of Medical Devices
|November 17, 2009
PubMed
Summary
This summary is machine-generated.

Adult stem cells show promise for tissue engineering, with hair follicle- and adipose-derived stem cells emerging as strong candidates. These cells offer potency and easier extraction compared to traditional bone marrow stem cells.

More Related Videos

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
09:31

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

Published on: March 30, 2018

Use of Human Perivascular Stem Cells for Bone Regeneration
07:05

Use of Human Perivascular Stem Cells for Bone Regeneration

Published on: May 25, 2012

Related Experiment Videos

Last Updated: Jun 18, 2026

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model
13:04

Generation and Grafting of Tissue-engineered Vessels in a Mouse Model

Published on: March 18, 2015

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats
09:31

Evaluation of Stem Cell Therapies in a Bilateral Patellar Tendon Injury Model in Rats

Published on: March 30, 2018

Use of Human Perivascular Stem Cells for Bone Regeneration
07:05

Use of Human Perivascular Stem Cells for Bone Regeneration

Published on: May 25, 2012

Area of Science:

  • Regenerative Medicine
  • Biomaterials Science
  • Stem Cell Biology

Background:

  • Tissue engineering aims to regenerate tissues but faces challenges in clinical translation of adult stem cells.
  • Adult stem cells, particularly those from bone marrow, are widely used but may not be optimal for future applications.
  • Recent findings highlight the transdifferentiation potential of specific adult stem cell populations.

Purpose of the Study:

  • To review and assess promising adult stem cell populations for tissue engineering applications.
  • To compare the potential of hair follicle- and adipose-derived stem cells against traditional bone marrow stem cells.
  • To identify key research avenues for advancing adult stem cell-based tissue engineering.

Main Methods:

  • Literature review of studies on adult stem cell differentiation and tissue engineering.
  • Comparative analysis of stem cell sources based on potency, abundance, and extraction methods.
  • Evaluation of in vitro and in vivo tissue engineering successes using different stem cell types.

Main Results:

  • Hair follicle- and adipose-derived stem cells have demonstrated successful tissue engineering in vitro and in vivo.
  • These alternative stem cell sources offer advantages in potency, abundance, and non-invasive extraction.
  • Bone marrow-derived stem cells may be superseded by these newer candidates in future tissue engineering.

Conclusions:

  • Hair follicle- and adipose-derived stem cells represent highly promising candidates for advancing tissue engineering.
  • Their properties suggest a significant potential for clinical translation and the creation of biomimetic tissues.
  • Further research into these stem cell populations is crucial for realizing the full potential of tissue engineering.