Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
Assessment of Diffusion and Perfusion01:17

Assessment of Diffusion and Perfusion

Understanding and evaluating diffusion and perfusion is critical in assessing a patient's respiratory and circulatory health. These processes play key roles in maintaining the body's internal environment, ensuring that tissues receive adequate oxygen while waste products are efficiently removed.
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this principle...
Diffusion01:12

Diffusion

Diffusion is the passive movement of substances down their concentration gradients—requiring no expenditure of cellular energy. Substances, such as molecules or ions, diffuse from an area of high concentration to an area of low concentration in the cytosol or across membranes. Eventually, the concentration will even out, with the substance moving randomly but causing no net change in concentration. Such a state is called dynamic equilibrium, which is essential for maintaining overall...
Imaging Studies for Cardiovascular System IV: CMRI01:21

Imaging Studies for Cardiovascular System IV: CMRI

Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Carvedilol Exerts Cardioprotective Effects Against Doxorubicin Toxicity via Autophagy Modulation and Energetics Restoration.

Pharmaceuticals (Basel, Switzerland)·2026
Same author

Mapping subarachnoid cerebrospinal fluid circulation in the human brain.

bioRxiv : the preprint server for biology·2026
Same author

Quantitative and Morphometric Measures in the Human Hippocampal Tail Using Ex Vivo Imaging Validated With Histology.

Hippocampus·2026
Same author

Water/Fat Separated Echo Planar Time-Resolved Imaging (WFS-EPTI) for Distortion-Free Multi-Contrast MRI.

Magnetic resonance in medicine·2026
Same author

Toward Skin-like Sensors: Stretchable Conductive Gels for Triboelectric Applications.

Gels (Basel, Switzerland)·2026
Same author

Diffusion Tensor MRI of the Heart: The Toolbox Continues to Grow.

Circulation. Cardiovascular imaging·2026

Related Experiment Video

Updated: Jun 18, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Diffusion MR tractography of the heart.

David E Sosnovik1, Ruopeng Wang, Guangping Dai

  • 1Martinos Center for Biomedical Imaging, Massachusetts General Hospital, Harvard Medical School, Boston MA, USA. sosnovik@nmr.mgh.harvard.edu

Journal of Cardiovascular Magnetic Resonance : Official Journal of the Society for Cardiovascular Magnetic Resonance
|November 17, 2009
PubMed
Summary

Diffusion MRI tractography, especially diffusion spectrum imaging (DSI), visualizes myocardial fiber architecture. This technique aids in understanding changes in ischemic heart disease and heart failure.

More Related Videos

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Related Experiment Videos

Last Updated: Jun 18, 2026

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging
17:06

Co-analysis of Brain Structure and Function using fMRI and Diffusion-weighted Imaging

Published on: November 8, 2012

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery
09:53

Role of Diffusion MRI Tractography in Endoscopic Endonasal Skull Base Surgery

Published on: July 5, 2021

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases
09:33

Diffusion Tensor Magnetic Resonance Imaging in the Analysis of Neurodegenerative Diseases

Published on: July 28, 2013

Area of Science:

  • Cardiovascular Imaging
  • Biomedical Engineering
  • Medical Physics

Background:

  • Myocardial histology reveals complex, crossing helical fiber tracts.
  • Myocardial fiber architecture is altered in conditions like ischemic heart disease and heart failure.
  • Diffusion-encoded Magnetic Resonance (MR) imaging offers non-destructive visualization of these architectural changes.

Purpose of the Study:

  • To review the physical principles of diffusion tractography in the myocardium.
  • To discuss various diffusion-encoding techniques, emphasizing Diffusion Spectrum Imaging (DSI).
  • To explore the clinical applications of DSI in ischemic heart disease and future translation.

Main Methods:

  • Review of diffusion-encoded MR imaging techniques.
  • Focus on Diffusion Spectrum Imaging (DSI) for its suitability in generating 3D tractograms.
  • Analysis of DSI's application in imaging myocardial myofiber architecture.

Main Results:

  • Diffusion MRI, particularly DSI, enables non-destructive imaging of myocardial fiber architecture.
  • DSI is well-suited for creating detailed 3D tractograms of myofibers.
  • Existing studies demonstrate the application of DSI in assessing myocardial changes in ischemic heart disease.

Conclusions:

  • Diffusion MRI tractography, with an emphasis on DSI, is a powerful tool for visualizing myocardial architecture.
  • DSI facilitates the study of architectural alterations in cardiac diseases.
  • Further development is needed for widespread clinical adoption of diffusion MR tractography in cardiology.