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Updated: Jun 18, 2026

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800 Laparoscopic partial nephrectomies: a single surgeon series.

Inderbir S Gill1, Kazumi Kamoi, Monish Aron

  • 1USC Institute of Urology, Keck School of Medicine, University of Southern California, Los Angeles, California, USA.

The Journal of Urology
|November 17, 2009
PubMed
Summary

Laparoscopic partial nephrectomy outcomes improved significantly from 1999 to 2008, with shorter ischemia times and better renal function despite more complex tumors. This technique is now standard for most kidney tumors.

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Area of Science:

  • Urology
  • Surgical Oncology

Background:

  • Laparoscopic partial nephrectomy (LPN) has become a cornerstone for kidney cancer treatment.
  • Evolution of surgical techniques and patient selection criteria may impact outcomes.

Purpose of the Study:

  • To evaluate the evolution of patient and tumor selection, perioperative outcomes, complications, and renal function in 800 LPNs over a 9-year period (1999-2008).

Main Methods:

  • Retrospective analysis of 800 LPNs performed by a single surgeon, divided into three chronological eras (1999-2003, 2004-2006, 2007-2008).
  • Evaluation of prospectively collected data on tumor characteristics, perioperative outcomes, and renal function.

Main Results:

  • Tumors in the most recent era were larger and more centrally located, indicating increased complexity.

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  • Warm ischemia time decreased significantly (31.9 to 14.4 minutes), and postoperative complication rates were lower.
  • Renal function outcomes improved, with a lesser decrease in estimated glomerular filtration rate (18% to 11%) in the most recent era.

    • Conclusions:

    • Despite increasing tumor complexity, key outcomes of LPN, including ischemia time, complication rates, and renal function, significantly improved over the study period.
    • LPN is now routinely offered for tumors previously treated with open partial nephrectomy.