Related Experiment Video
Updated: Jun 18, 2026
07:50
A Metadata Extraction Approach for Clinical Case Reports to Enable Advanced Understanding of Biomedical Concepts
Published on: September 20, 2018
Cerebral infarct due to meningovascular neurobrucellosis: a case report
Saime Ay1, Birkan Sonel Tur, Sehim Kutlay
1Department of Physical Medicine and Rehabilitation, Ufuk University School of Medicine, Ankara, Turkey. saimeay@yahoo.com
Abstract:
Brucellosis is a common and multisystemic zoonotic infectious disease. Central nervous system involvement is rarely seen in brucellosis, with an incidence of 0.5-25%. The aim of this report is to underline the importance of brucellosis, which is an endemic infection in our country, during the diagnostic evaluation of stroke.
Insights
Brucellosis, a zoonotic disease, can rarely affect the central nervous system. This report highlights the importance of considering brucellosis in stroke evaluations, especially in endemic areas.
Area of Science:
- Infectious Diseases
- Neurology
- Public Health
Background:
- Brucellosis is a prevalent zoonotic infection with multisystemic manifestations.
- Central nervous system (CNS) involvement in brucellosis is infrequent, occurring in 0.5-25% of cases.
- Stroke is a significant neurological event requiring thorough etiological investigation.
Observation:
- This report focuses on a case where brucellosis was a contributing factor to stroke.
- Brucellosis, though rare, can present with neurological complications mimicking other conditions.
- The endemic nature of brucellosis in the region necessitates its consideration in differential diagnoses.
Findings:
- Central nervous system brucellosis can manifest in various ways, including stroke.
- Timely diagnosis of brucellosis is crucial for effective treatment and prevention of complications.
- Diagnostic evaluation for stroke should include screening for endemic infectious diseases like brucellosis.
Implications:
- Clinicians should maintain a high index of suspicion for brucellosis in patients presenting with stroke, particularly in endemic regions.
- Integrating infectious disease screening into stroke workups can improve diagnostic accuracy.
- Raising awareness about neurobrucellosis is vital for public health strategies in endemic areas.
Related Concept Videos
01:22Bacterial Meningitis I: Introduction
Bacterial meningitis is a severe, life-threatening inflammation of the meninges, particularly the pia mater and arachnoid mater, affecting the subarachnoid space, ventricles, and cerebrospinal fluid (CSF). If untreated, it can lead to significant neurological complications or death.Causative AgentsCommon pathogens vary with age and immune status. In adults, major organisms include Streptococcus pneumoniae, Neisseria meningitidis, and Haemophilus influenzae. Streptococcus agalactiae (group B...
01:26Brain Abscess l: Introduction
A brain abscess is a focal, intracerebral infection characterized by a localized collection of pus within the brain parenchyma, resulting from microbial invasion and the body’s inflammatory response. It progresses through stages: early and late cerebritis, followed by early and late capsule formation, reflecting tissue destruction, immune response, and eventual encapsulation.Etiology and PathogenesisCausative organisms vary with source and host factors, often involving polymicrobial infections,...
01:27Cryptococcal Meningitis
Cryptococcal meningitis is a life-threatening opportunistic infection predominantly associated with HIV/AIDS, accounting for over 100,000 deaths annually worldwide. However, it also affects individuals with other forms of immunosuppression, including those undergoing immunosuppressive therapy, organ transplant recipients, patients with innate immunodeficiencies, and individuals with hematological disorders. The infection is caused mainly by Cryptococcus neoformans and Cryptococcus gattii,...
01:22Cerebral Edema ll: Pathophysiology
Vasogenic edema is a major form of cerebral edema characterized by abnormal accumulation of fluid in the brain’s extracellular space due to disruption of the blood–brain barrier (BBB). The BBB is a specialized structure composed of endothelial cells connected by tight junctions, supported by astrocytic endfeet and a basement membrane. Under normal conditions, it tightly regulates the movement of ions, proteins, and solutes between the bloodstream and brain parenchyma. When this barrier loses...
01:24Bacterial Meningitis
Bacterial meningitis is a severe infectious disease involving inflammation of the meninges, the protective membranes surrounding the brain and spinal cord. It occurs when pathogenic bacteria cross the blood–brain barrier and enter the cerebrospinal fluid. Common causative organisms include Neisseria meningitidis, Streptococcus pneumoniae, Haemophilus influenzae type b, Listeria monocytogenes, and Escherichia coli K1. The exact route of entry varies by pathogen and host condition.Routes of Entry...
01:18Viral Meningitis
Viral meningitis is the most common form of meningitis and is often referred to as aseptic meningitis to indicate the absence of bacterial involvement. It is generally milder than bacterial meningitis, with symptoms including fever, headache, stiff neck, drowsiness, nausea, photophobia, and vomiting. Rarely, more severe manifestations or death may occur. Common causative agents include enteroviruses, particularly coxsackie A and B viruses and echoviruses, all members of the Enterovirus genus...