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Updated: Jun 18, 2026

A 3D Organotypic Melanoma Spheroid Skin Model
Published on: May 18, 2018
Systemic therapy for cutaneous melanoma
Jonathan Treisman1, Nina Garlie
1Immunotherapy Program, Aurora St Luke's Medical Center, 2900 West Oklahoma Avenue, Milwaukee, WI 53215, USA. jtreisman@gmail.com
Abstract:
This article provides a review of the current medical management of patients with high-risk and metastatic cutaneous melanoma, including a review of the use of adjuvant interferon therapy and a discussion of adjuvant treatments under evaluation. The use of standard chemotherapeutic agents for metastatic disease is discussed, with an emphasis on developmental therapeutics using targeted agents. This discussion includes a review of the immune therapy for metastatic melanoma, including newer immunomodulatory agents and cellular therapeutics that are expected to significantly impact the care of these patients.
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