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Aerial oxidation of hydrazines to nitrosamines
G Lunn1, E B Sansone, A W Andrews
1Environmental Control and Research Program, NCI-Frederick Cancer Research and Development Center, Maryland 21702-1201.
Environmental and Molecular Mutagenesis
|January 1, 1991
Abstract:
When 1,1-dimethylhydrazine and N-aminopiperidine were deliberately exposed to air substantial amounts of the corresponding carcinogenic nitrosamines were formed. Unoxidized samples of 1,1-dimethylhydrazine were not mutagenic while oxidized samples (which contained much higher levels of nitrosamines) were mutagenic. Both unoxidized and oxidized samples of N-aminopiperidine were mutagenic.