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The Goeckerman Regimen for the Treatment of Moderate to Severe Psoriasis
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Published on: July 11, 2013

Generalized pustular psoriasis of pregnancy successfully treated with cyclosporine

Debeeka Hazarika1

  • 1Department of Dematology, Assam Medical College and Hospital, Dibrugarh, Assam, India. urbashium@rediffmail.com

Indian Journal of Dermatology, Venereology and Leprology
|November 17, 2009
PubMed

Two multigravidae aged 27 and 29 years, with previous uneventful pregnancies, second being psoriatic, reported at 24 and 28 weeks of pregnancies, with generalized pustular lesions. Laboratory findings, including serum calcium were normal. Ultrasonography showed normal fetal growth. Histopathology confirmed pustular psoriasis. Patients were put on cyclosporine 3 mg/ kg weight/ day after failure of an initial systemic steroid. Blood pressure, pulse, and fetal heart sounds were recorded every 12 hours, and ultrasonography and blood parameters, biweekly. Cyclosporine was tapered and stopped after delivery of two healthy babies at 38 weeks. We conclude that cyclosporine can be an option in the management of pustular psoriasis of pregnancy or psoriasis with pustulation in pregnancy.

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