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Related Concept Videos

Yellow Fever01:18

Yellow Fever

Yellow fever is a viral hemorrhagic disease caused by the yellow fever virus (YFV), a member of the Flaviviridae family. It is transmitted primarily by Aedes and Haemagogus mosquitoes in tropical and subtropical regions of Africa and South America. After transmission through a mosquito bite, the virus initially replicates in skin-resident immune cells such as dendritic cells and macrophages. These cells then migrate to the lymph nodes, where viral replication increases, eventually leading to...
Arboviral Encephalitis01:25

Arboviral Encephalitis

Arboviral encephalitis refers to brain inflammation caused by arthropod-borne viruses, particularly those transmitted through mosquito vectors. Among these, West Nile virus (WNV), a member of the Flaviviridae family, is a significant public health concern. WNV is an enveloped, positive-sense, single-stranded RNA virus. Human infection typically begins when an infected mosquito introduces the virus into the dermis during feeding. The primary transmission cycle involves birds as amplifying hosts...
Infectious Diseases and Their Occurrence01:28

Infectious Diseases and Their Occurrence

Infectious diseases appear in populations through various transmission patterns, influenced by pathogen characteristics, population immunity, environmental conditions, and social behavior. Understanding these patterns is essential for effective public health surveillance and intervention. These categories—sporadic, outbreak, epidemic, pandemic, and endemic—help frame the nature and scope of disease events.Sporadic diseases occur irregularly and infrequently, without a predictable temporal or...
Malaria01:29

Malaria

Malaria pathogenesis in humans reflects a delicate interplay between parasite biology and host response. Clinical illness reflects a host’s immune response to the parasite’s asexual replication cycle, which is often asymptomatic in individuals with partial immunity. From the parasite's perspective, transmission between mosquito and human with minimal host pathology is evolutionarily advantageous. Among the six Plasmodium species infecting humans, P. falciparum and P. vivax dominate in global...
Rocky Mountain Spotted Fever01:26

Rocky Mountain Spotted Fever

Rocky Mountain Spotted Fever (RMSF) is a severe tick-borne illness caused by Rickettsia rickettsii, a Gram-negative, coccobacillary bacterium. This pathogen is an obligate intracellular parasite, requiring a host cell for replication. Transmission occurs through the bite of an infected tick. In the United States, the most important vectors are Dermacentor variabilis (American dog tick) and Dermacentor andersoni (Rocky Mountain wood tick), though other tick species may also serve as vectors.
Encephalitis l: Introduction01:19

Encephalitis l: Introduction

Encephalitis is inflammation of the brain parenchyma, most often due to infections or autoimmune processes. It presents with neuropsychiatric features such as fever, altered mental status, behavioral changes, cognitive dysfunction, seizures, focal deficits, and sometimes autonomic instability. In some cases, the meninges are also involved, resulting in meningoencephalitis.Infectious CausesInfectious encephalitis is most commonly viral but can also result from bacterial, fungal, or parasitic...

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Related Experiment Video

Updated: Jun 18, 2026

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
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Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Published on: May 31, 2020

Imported Dengue Fever: an important reemerging disease.

Malachi Courtney1, Avinash K Shetty

  • 1Department of Pediatrics, Wake Forest University Health Sciences, Winston-Salem, NC 27157, USA.

Pediatric Emergency Care
|November 17, 2009
PubMed
Summary

Dengue fever, a mosquito-borne illness, presents a diagnostic challenge for travelers returning from the tropics. Early recognition is crucial for managing this reemerging infectious disease.

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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
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A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

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Last Updated: Jun 18, 2026

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus
10:35

Vector Competence Analyses on Aedes aegypti Mosquitoes using Zika Virus

Published on: May 31, 2020

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease
04:23

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Area of Science:

  • Tropical medicine
  • Infectious diseases
  • Public health

Background:

  • Fever in returned travelers from tropical regions poses diagnostic challenges due to potentially severe infections like malaria and dengue.
  • Dengue fever is a significant global mosquito-transmitted viral infection.
  • Dengue is reemerging in US tropical and subtropical areas and is underreported along the Mexican border.

Observation:

  • * A case of imported dengue fever in a 15-year-old boy returning from Guatemala is presented.
  • * The patient experienced fever, a common symptom requiring differential diagnosis.

Findings:

  • * Dengue fever, a mosquito-borne viral infection, is of global importance and reemerging in the US.
  • * The case highlights the need to consider dengue in febrile travelers.
  • * Epidemiology, clinical features, diagnosis, and prevention strategies for dengue are reviewed.

Implications:

  • * Clinicians must consider dengue in the differential diagnosis of febrile illnesses in children returning from endemic areas.
  • * Public health awareness and traveler education are vital for prevention.
  • * Prompt diagnosis and management can reduce morbidity and mortality associated with dengue fever.