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Updated: Jun 18, 2026

Identification and Dissection of Diverse Mouse Adipose Depots
Published on: July 11, 2019
The road from discovery to clinic: adiponectin as a biomarker of metabolic status
1Touchstone Diabetes Center, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, Texas, USA.
Abstract:
Biomarkers are globally used to monitor clinical responses to therapeutic and lifestyle interventions. The adipocyte-derived hormone adiponectin is recognized as a promising new biomarker owing to its many associations with components of the metabolic syndrome. The study described by Wagner and colleagues in this issue offers a first example of how a large-scale effort in the context of a cross-company collaborative study in the pharmaceutical industry can offer a powerful tool for the further validation of a new biomarker in the context of pharmacological intervention with peroxisome proliferator-activated receptor-gamma (PPAR-gamma) agonists.
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