The human genome initiative. There are two large questions

Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.

Oncogene·2014

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence.

Oncogene·2010

The evolving portrait of cancer metastasis.

Cold Spring Harbor symposia on quantitative biology·2006

Derivation of human tumor cells in vitro without widespread genomic instability.

Cancer research·2001

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.

Cell·2001

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation.

Nature cell biology·2001

Polygonum cuspidatum Exosome-Like Nanovesicles Alleviate Hypoxic Pulmonary Hypertension by Stabilizing PON1 to Inhibit MAPK-Mediated PASMC Phenotypic Switching.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

LCN2-Driven Fibroblast Ferroptosis-Associated Injury Promotes Keratinocyte Proliferation via Lipid Peroxidation Signaling in Psoriasis.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Protective Effects and Mechanisms of Extracellular Vesicles in Remote Ischemic Preconditioning on Renal Injury Induced by Inflammation.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Integrative Multi-omics Analysis for Prioritization of Candidate Genes in Polycystic Ovary Syndrome.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Magnesium Attenuates Renal Senescence and Fibrosis With Reduced DNA Damage Response and H3K4me3 Enrichment at the p16INK4a Promoter.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Integration of Bulk RNA Sequencing and Single-Cell Sequencing to Identify Prognostic Genes Associated With MCDRGs in Neuroblastoma.

FASEB journal : official publication of the Federation of American Societies for Experimental Biology·2026

Clinical and Molecular Findings in Two Siblings with a Novel Homozygous DCAF17 Frameshift Variant and Review of the Literature: A Case Report.

Molecular syndromology·2026

Integrative methylome and transcriptome analysis reveals genotype and sequence context-specific responses to aluminum stress in rice.

Frontiers in plant science·2026

AdaBoost-based differential diagnosis of gouty arthritis and rheumatoid arthritis: model construction, temporal validation, and SHAP visualization.

Frontiers in medicine·2026

Refining genetic discoveries of group knockoffs via a feature-level filter.

Journal of the Royal Statistical Society. Series C, Applied statistics·2026

Spatial decoupling of plaque and circulating immune programs defines a robust gene signature in atherosclerosis: A multi-cohort integrative analysis.

Medicine·2026

Causal relationship between dietary habits and low hand grip strength: A Mendelian randomization study.

Medicine·2026

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The human genome initiative. There are two large questions

Related Concept Videos

Thrombospondin-1 repression is mediated via distinct mechanisms in fibroblasts and epithelial cells.

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence.

The evolving portrait of cancer metastasis.

Derivation of human tumor cells in vitro without widespread genomic instability.

hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase.

TGF-beta-induced apoptosis is mediated by the adapter protein Daxx that facilitates JNK activation.

Polygonum cuspidatum Exosome-Like Nanovesicles Alleviate Hypoxic Pulmonary Hypertension by Stabilizing PON1 to Inhibit MAPK-Mediated PASMC Phenotypic Switching.

LCN2-Driven Fibroblast Ferroptosis-Associated Injury Promotes Keratinocyte Proliferation via Lipid Peroxidation Signaling in Psoriasis.

Protective Effects and Mechanisms of Extracellular Vesicles in Remote Ischemic Preconditioning on Renal Injury Induced by Inflammation.

Integrative Multi-omics Analysis for Prioritization of Candidate Genes in Polycystic Ovary Syndrome.

Magnesium Attenuates Renal Senescence and Fibrosis With Reduced DNA Damage Response and H3K4me3 Enrichment at the p16INK4a Promoter.

Integration of Bulk RNA Sequencing and Single-Cell Sequencing to Identify Prognostic Genes Associated With MCDRGs in Neuroblastoma.

Clinical and Molecular Findings in Two Siblings with a Novel Homozygous DCAF17 Frameshift Variant and Review of the Literature: A Case Report.

Integrative methylome and transcriptome analysis reveals genotype and sequence context-specific responses to aluminum stress in rice.

AdaBoost-based differential diagnosis of gouty arthritis and rheumatoid arthritis: model construction, temporal validation, and SHAP visualization.

Refining genetic discoveries of group knockoffs via a feature-level filter.

Spatial decoupling of plaque and circulating immune programs defines a robust gene signature in atherosclerosis: A multi-cohort integrative analysis.

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The human genome initiative. There are two large questions

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