Related Experiment Video
Updated: Jun 18, 2026

In Vivo Confocal Microscopy in the Diagnosis and Management of Dry Eye: A Focus on Imaging Protocols and Interpretation
Published on: November 11, 2025
[Morphological characteristics of actinomycotic dacryocanaliculitis]
Abstract:
The paper presents the results of pathohistological studies of the contents of the lacrimal canaliculi and the fragments of their walls, obtained at canaliculotomy in 25 patients. This permitted 14 cases of actinomycotic dacryocanaliculitis to be identified as drusens of the ray fungus Actinomyces israelii had been found. The reactive structural changes found in the wall of the lacrimal canaliculi due to the presence of fungal infection and foreign bodies in their lumen are described. A morphological study is shown to be effective in revealing the actinomycotic etiology of dacryocanaliculitis.
Insights
This study identified actinomycotic dacryocanaliculitis in 14 patients using pathohistological analysis. Morphological examination effectively revealed fungal infections and structural changes in the lacrimal canaliculi.
Area of Science:
- Ophthalmology
- Pathology
- Microbiology
Background:
- Dacryocanaliculitis is an infection of the tear drainage system.
- Actinomycosis, caused by Actinomyces israelii, can affect the lacrimal canaliculi.
- Accurate diagnosis is crucial for effective treatment.
Purpose of the Study:
- To investigate the pathological findings in patients with dacryocanaliculitis.
- To determine the prevalence of actinomycotic infections in lacrimal canaliculi.
- To evaluate the efficacy of morphological studies in diagnosing the condition.
Main Methods:
- Pathohistological examination of lacrimal canaliculus contents and wall fragments.
- Surgical specimens obtained via canaliculotomy from 25 patients.
- Microscopic identification of Actinomyces israelii (ray fungus) and reactive changes.
Main Results:
- Actinomycotic dacryocanaliculitis was identified in 14 out of 25 patients.
- Drusen of Actinomyces israelii were found in the affected canaliculi.
- Reactive structural changes in the lacrimal canaliculi wall were observed due to fungal infection and foreign bodies.
Conclusions:
- Morphological study is a highly effective method for diagnosing actinomycotic dacryocanaliculitis.
- Fungal infection by Actinomyces israelii is a significant cause of dacryocanaliculitis.
- Understanding structural changes aids in diagnosis and management.
Related Concept Videos
Bacterial Phylum Actinobacteria
Cryptococcal Meningitis
Acne Infection
Microbiome of the Eye
Brain Abscess l: Introduction

