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Updated: Jun 18, 2026

Modeling Neonatal Intraventricular Hemorrhage Through Intraventricular Injection of Hemoglobin

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Published on: August 25, 2022

[Neonatal Volkmann's syndrome].

M Dandurand¹, B Michel, C Fabre

¹Service de dermatologie, hôpital Caremeau, CHU de Nîmes, place du Professeur-R.-Debré, 30029 Nîmes cedex 9, France. michel.dandurand@chu-nimes.fr

Annales De Dermatologie Et De Venereologie

|November 18, 2009

Summary

Congenital Volkmann's ischaemic contracture (CVIC) is a rare condition. This case highlights shoulder dystocia and maternal medication as potential triggers for CVIC, emphasizing early MR angiography for diagnosis.

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Area of Science:

Neonatal Medicine
Pediatric Surgery
Vascular Surgery

Background:

Acute limb compartment syndrome, or Volkmann's ischaemic contracture, results from elevated pressure within a fascial space, causing nerve and muscle ischemia.
Congenital Volkmann's ischaemic contracture (CVIC) is an exceptionally rare presentation of this condition.

Observation:

A neonate presented with congenital Volkmann's ischaemic contracture of the left arm, characterized by edema, skin necrosis, and cyanosis.
Delivery was complicated by shoulder dystocia, and the mother had taken prazepam, olanzapine, and valpromide during pregnancy.
MR angiography revealed extensive soft tissue edema, arterial compression, and reduced blood flow, necessitating a fasciotomy.

Findings:

This case underscores the diagnostic utility of early MR angiography in identifying extensive edema, arterial compression, and compromised perfusion in neonatal compartment syndrome.
Shoulder dystocia was identified as a novel traumatic factor contributing to CVIC.
Maternal use of prazepam, a benzodiazepine, was implicated as a potential etiological factor, possibly inducing hypotonia and malposition leading to crush injury.

Implications:

The findings suggest that maternal medication, particularly long-acting benzodiazepines, may play a role in the pathogenesis of neonatal compartment syndrome.
Early diagnosis and intervention, guided by advanced imaging like MR angiography, are crucial for managing CVIC.
This case broadens the understanding of CVIC etiology, incorporating obstetric complications and maternal pharmacotherapy.