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Related Concept Videos

Oligosaccharide Assembly01:24

Oligosaccharide Assembly

Protein glycosylation starts in the ER lumen and continues in the Golgi apparatus. Glycosyltransferases catalyze the addition of sugar molecules or glycosylation of proteins. Usually, these enzymes add sugars to the hydroxyl groups of selected serine or threonine residues to form O-linked glycans or the amino groups of asparagine residues to form N-linked glycans. Different positions on the same polypeptide chain can contain differently linked glycans.
Multiple sugar molecules that may or may...
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Cell adhesion is  an essential aspect of multicellularity. While stable cell interactions usually occur between cells of the same type, transient cell interactions occur between cells of different tissue types, such as between neutrophils and endothelial cells. Selectins are one class of cell adhesion molecules (CAMs) that bind carbohydrate ligands to form transient cell adhesion. They are rod-like proteins with a long extracellular part of variable length ending with the lectin domain, which...

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Related Experiment Video

Updated: Jun 18, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
08:07

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

Mannose-binding lectin levels in endometriosis.

Kemal Ozerkan1, Barbaros Oral, Gürkan Uncu

  • 1Department of Obstetrics and Gynecology, Uludağ University, Bursa, Turkey. doctorkemal@yahoo.com

Fertility and Sterility
|November 18, 2009
PubMed
Summary

Serum mannose-binding lectin levels are similar in women with and without endometriosis. This suggests mannose-binding lectin may not play a direct role in the development of endometriosis, despite its role in inflammation.

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Last Updated: Jun 18, 2026

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
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Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage
05:16

Multiplexed Fluorescent Immunohistochemical Staining of Four Endometrial Immune Cell Types in Recurrent Miscarriage

Published on: August 4, 2021

Area of Science:

  • Immunology
  • Reproductive Medicine
  • Gynecology

Background:

  • Mannose-binding lectin (MBL) is a key component of the innate immune system.
  • Endometriosis is a chronic inflammatory condition affecting women of reproductive age.

Purpose of the Study:

  • To investigate the association between serum mannose-binding lectin concentrations and endometriosis.
  • To determine if MBL plays a role in the pathogenesis of endometriosis.

Main Methods:

  • Serum samples were collected from patients diagnosed with endometriosis and a control group without the condition.
  • Mannose-binding lectin concentrations were measured using enzyme-linked immunosorbent assay (ELISA).

Main Results:

  • No significant difference was observed in serum MBL levels between women with endometriosis and those without.
  • MBL levels did not correlate with the severity or stage of endometriosis.

Conclusions:

  • Serum mannose-binding lectin concentrations do not differ between patients with and without endometriosis.
  • MBL may not be directly involved in the pathogenesis of endometriosis, although it could modulate inflammatory responses.