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Updated: Jun 18, 2026

Isolation of Endothelial Progenitor Cells from Human Umbilical Cord Blood
Published on: September 14, 2017
Endothelial progenitor cells: their potential in the placental vasculature and related complications
P I Sipos1, I P Crocker, C A Hubel
1Maternal and Fetal Health Research Group, The University of Manchester, Research Floor, St Mary's Hospital, Oxford Road, Manchester, M13 9WL, UK. Peter.Sipos@manchester.ac.uk
Abstract:
Endothelial progenitor cells (EPCs) have received significant attention in recent times. A role for EPCs has been suggested in a range of pathologies and some recent studies of EPCs in pregnancy have been published. This review provides a guide to the confusing field of EPCs. Attention is paid to their phenotyping, as although elementary this remains a highly debated topic. The current understanding of different subtypes and physiological role of EPCs in the placenta, fetus and adult are also considered. An overview is given as to role of EPC's in the pathophysiology of different disease states and the possible therapeutic and diagnostic applications expected from EPC-related research in obstetrics.
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