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Updated: Jun 18, 2026

A Standardized Procedure of Dressing Management for Toxic Epidermal Necrolysis
Published on: March 14, 2025
Clinical applications for the use of enzymatic debriding ointment and broad-spectrum bacteriostatic foam dressing
Stanley Keith McCallon1, Jennifer Hurlow
1Department of Physical Therapy, Louisiana State University Health Sciences Center, School of Allied Health Professions, Shreveport, LA 71130, USA. smccal@lsuhsc.edu
Abstract:
The optimal management of a chronic, nonhealing wound is challenging to experienced and novice clinicians alike. Treatment must be individualized, but principles of wound bed preparation, including debridement of necrotic tissue, maintenance of moisture in the wound, and prevention of bacterial overgrowth, guide the management of nonhealing wounds caused by a variety of different etiologies. This article summarizes our experiences with 2 products, collagenase ointment and crystal violet/methylene blue-impregnated foam, in the treatment of 3 nonhealing wounds.
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