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Updated: Jun 18, 2026

Duodenal-Jejunal Bypass Surgery in Diet-Induced Obese Diabetic Mice
Published on: October 18, 2024
Duodenal bypass does not decrease glucose levels of lean individuals with gastric cancer submitted to partial or
Fernando A Herbella1, Ana C Tineli, Jorge L Wilson
1Department of Surgery, Division of Esophagus and Stomach, Universidade Federal de São Paulo, São Paulo, SP, Brazil. herbella.dcir@unifesp.epm.br
Abstract:
Change in glucose metabolism after bariatric operations may be credited to duodenal bypass. This study aims to evaluate the effect of duodenal bypass on glucose levels in lean individuals submitted to gastrectomy for gastric cancer. We reviewed 56 non-diabetic and 6 diabetic patients submitted to gastrectomy and Roux-en-Y for gastric cancer (partial gastrectomy in 66%/total gastrectomy in 34%). Glucose levels were not significantly altered after operation (P = 0.5). Diabetes control was improved in one patient with oral medication. In conclusion, duodenal bypass do not decrease glucose levels in lean individuals treated for gastric cancer.

