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Related Experiment Videos

Diffuse large B-cell lymphoma presenting as piriformis syndrome.

Byoung Seok Ye1, Il Nam Sunwoo, Bum Chun Suh

  • 1Department of Neurology, Yonsei University College of Medicine, Seoul 120-752, Korea.

Muscle & Nerve
|November 18, 2009
PubMed
Summary

Piriformis syndrome can mimic lymphoma. This case highlights neurolymphomatosis as a rare cause of secondary piriformis syndrome, emphasizing the need for broader differential diagnoses.

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Area of Science:

  • Neurology
  • Oncology
  • Orthopedics

Background:

  • Piriformis syndrome (PS) is a rare condition causing buttock pain and radiating paresthesia.
  • Sciatica is a common symptom that can be associated with PS.

Observation:

  • A patient presented with sciatica clinically suspected to be PS.
  • Diagnostic work-up revealed diffuse large B-cell lymphoma with neurolymphomatosis (NL).

Findings:

  • This is the first reported case of neurolymphomatosis presenting as piriformis syndrome.
  • Neurolymphomatosis is identified as a potential cause of secondary PS.

Implications:

  • This case broadens the differential diagnosis for piriformis syndrome.
  • Highlights the importance of considering malignancy in unexplained neurological symptoms.
  • Suggests neurolymphomatosis as a treatable cause of secondary piriformis syndrome.