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Magnetic Resonance Imaging of Multiple Sclerosis at 7.0 Tesla
Published on: February 19, 2021
MRI using radiofrequency magnetic field phase gradients.
Jonathan C Sharp1, Scott B King
1Institute for Biodiagnostics (West), National Research Council of Canada, Calgary, Alberta, Canada. Jonathan.Sharp@nrc-cnrc.gc.ca
A new silent MRI method, Transmit Array Spatial Encoding (TRASE), uses radio-frequency (RF) phase gradients instead of expensive B0 gradients. This gradient-free approach enables silent, lower-cost MRI with potential for simplified equipment and novel imaging applications.
Area of Science:
- Magnetic Resonance Imaging
- Physics
- Biomedical Engineering
Background:
- Conventional MRI relies on B0 magnetic field gradients, which are costly, complex, and generate noise.
- B0 gradients can induce eddy currents in conductive materials, posing potential risks to patients.
Purpose of the Study:
- To introduce and demonstrate a novel, silent, gradient-free MRI technique called Transmit Array Spatial Encoding (TRASE).
- To explore the feasibility of TRASE for medical imaging applications by evaluating its performance and potential advantages.
Main Methods:
- TRASE utilizes phase gradients of the radio-frequency (RF) field for k-space traversal, eliminating the need for B0 gradients.
- One-dimensional imaging requires two RF phase gradients, while three are sufficient for two-dimensional imaging.
- Experimental validation was performed on a 0.2 T permanent magnet human MR system.
Main Results:
- Demonstrated successful one-dimensional and two-dimensional imaging and slice selection using TRASE.
- Achieved higher spatial resolution than RF receive coil array sensitivity encoding alone.
- Observed lower spatial resolution compared to conventional B0 gradient-based MRI.
Conclusions:
- TRASE offers a silent, gradient-free alternative for MRI, potentially reducing equipment costs and complexity.
- This technique is advantageous for applications prioritizing silent operation, lower cost, or unique imaging physics.
- Further development may enhance spatial resolution for broader clinical applicability.
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