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Updated: Jun 18, 2026

Microwave-Assisted Extraction of Phenolic Compounds and Antioxidants for Cosmetic Applications Using Polyol-Based Technology
Published on: August 23, 2024
Supramolecular phospholipids-polyphenolics interactions: the PHYTOSOME strategy to improve the bioavailability of
Ajay Semalty1, Mona Semalty, Mohan Singh Maniyari Rawat
1Department of Pharmaceutical Sciences, HNB Garhwal University Srinagar, Garhwal, India. semaltyajay@gmail.com
Abstract:
The poor and/or erratic oral bioavailability of polyphenolics can be improved using the PHYTOSOME delivery system, a strategy that enhances the rate and the extent of solubilization into aqueous intestinal fluids and the capacity to cross biomembranes. Phospholipids show affinity for polyphenolics, and form supramolecular adducts having a definite stoichiometry. This article reviews the preparation and characterization of PHYTOSOME complexes and their activity in various medicinal (cardiovascular, anti-inflammatory, hepatoprotective, anticancer) and cosmetic (skin aging) realms of application.
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