Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Related Concept Videos

Blood Transfusion

Blood Transfusion

Blood transfusion is a critical medical procedure that saves lives and treats various medical conditions. It involves transferring blood from a donor to a recipient. This process requires a thorough understanding of the ABO blood group system and its associated antigens and antibodies.
Blood Transfusion Overview
A blood transfusion is a medical procedure used to replace blood lost due to injury, surgery, or to treat conditions such as anemia or cancer. During a transfusion, donor blood is...

Blood Transfusion and Agglutination

Blood Transfusion and Agglutination

Blood transfusion is a therapeutic measure to restore the blood volume after extensive blood loss due to an accident or a medical procedure. Blood transfusion involves drawing a certain amount of blood from a suitable donor and infusing it into the recipient.
History
The history of blood transfusion dates back to the 17th century, when early attempts were made in animals. In 1818 James Blundell, a British doctor, performed the first successful human blood transfusion. Later in 1900, Karl...

Blood Typing

Blood Typing

Understanding an individual's blood group is a critical component of transfusion medicine. It ensures compatibility in blood transfusions, organ transplants, and even during pregnancy. Determining these blood groups involves the ABO and Rh blood typing systems, utilizing specific antigens and corresponding anti-sera to identify an individual's blood type.
Antigens are protein molecules that reside on the surface of red blood cells (RBCs). The ABO and Rh blood typing systems target antigens A,...

Blood Types

Blood Types

Human blood is classified into different types based on the presence of antigens on the red blood cell's surface and antibodies in the plasma. Proper identification of blood type is essential for successful blood transfusion. The International Society of Blood Transfusion has identified 38 human blood types based on the surface antigens on the red blood cells. The most common types are ABO, Rh, and MNS blood types.
ABO blood group
ABO antigens are glycoproteins encoded by genes present on...

Kidney Transplant I: Introduction

Kidney Transplant I: Introduction

A kidney transplant is a surgical approach that involves replacing a non-functioning kidney with a healthy one from a donor. This procedure is often a treatment option for end-stage renal disease (ESRD) patients. The method requires careful recipient selection, including evaluating various medical and psychosocial factors. These criteria vary between transplant centers but generally include assessments of the patient's overall health, adherence to medical recommendations, and lifestyle...

Bone Marrow Sampling and Transplants

Bone Marrow Sampling and Transplants

Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy the...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Are Management Practices for Pediatric Uncomplicated Acute Otitis Media Different on Weekends Versus Weekdays?

The Pediatric infectious disease journal·2026

Same author

Long-term otologic and auditory sequelae in children with recurrent acute otitis media.

International journal of pediatric otorhinolaryngology·2026

Same author

Beyond Traditional Pathogens: Clinical and Microbiologic Insights Into Atypical Pediatric Otitis Media.

The Pediatric infectious disease journal·2026

Same author

Low Alanine Aminotransferase Blood Activity, a Biomarker of Sarcopenia and Frailty, is Associated With Worse Post-Total Laryngectomy Clinical Outcomes. A Retrospective Analysis of 427 Patients.

Clinical otolaryngology : official journal of ENT-UK ; official journal of Netherlands Society for Oto-Rhino-Laryngology & Cervico-Facial Surgery·2025

Same author

Adenotonsillar Microbiome Shifts in Children With Obstructive Sleep Apnea Syndrome.

The Laryngoscope·2025

Same author

The Effect of an American Football Practice on Physical and Cognitive Performance and Recovery.

Journal of strength and conditioning research·2025

Search research articles

Related Experiment Video

Updated: Jun 18, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

Eager blood donor.

Tal Marom¹, Amit Rais, David Itskoviz

¹Medical Branch, Ground Forces Command, Israel Defense Forces, Israel. maromtal@013.net.il

Journal of Patient Safety

|November 19, 2009

Summary

This summary is machine-generated.

Frequent blood donation can lead to iron deficiency anemia, even in healthy individuals. This case highlights the importance of monitoring donation intervals to ensure donor safety and prevent adverse health effects.

More Related Videos

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Related Experiment Videos

Last Updated: Jun 18, 2026

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Detection of Residual Donor Erythroid Progenitor Cells after Hematopoietic Stem Cell Transplantation for Patients with Hemoglobinopathies

Published on: September 6, 2017

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Continuous Manual Exchange Transfusion for Patients with Sickle Cell Disease: An Efficient Method to Avoid Iron Overload

Published on: March 14, 2017

Area of Science:

Hematology
Transfusion Medicine
Public Health

Background:

Blood donor questionnaires are crucial for ensuring blood safety by screening donors.
Donation frequency is a key criterion to prevent adverse effects in repeat donors.
Iron deficiency anemia is a potential risk associated with frequent blood donations.

Observation:

A 19-year-old male soldier made five voluntary blood donations within 12 weeks.
The Israeli National Blood Services identified this donation pattern after the fifth donation.
The soldier was asymptomatic, but blood tests revealed iron deficiency anemia and low ferritin levels.

Findings:

The case revealed a gap in the blood donation screening process regarding donation frequency.
Despite frequent donations, the soldier experienced no significant short-term adverse health consequences.
Subclinical iron deficiency was detected, indicating a potential long-term risk.

Implications:

This case underscores the need for robust systems to track donation intervals and enforce safety guidelines.
It highlights the limitations of current blood donor screening protocols in identifying at-risk individuals.
Reinforcing donation interval policies is essential for maintaining donor health and the integrity of the blood supply.