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Thoracic Spinal Cord Hemisection Surgery and Open-Field Locomotor Assessment in the Rat
Published on: June 26, 2019
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Spinal cord protection and thoracic aortic surgery.
Ashish C Sinha1, Albert T Cheung
1University of Pennsylvania, Philadelphia, PA 19104-4283, USA.
Current Opinion in Anaesthesiology
|November 19, 2009
Summary
Spinal cord ischemia is a risk after aortic aneurysm repair. Early detection and treatment of spinal cord ischemia can prevent permanent paraplegia in high-risk patients.
Area of Science:
- Cardiovascular Surgery
- Neurology
- Vascular Surgery
Background:
- Spinal cord ischemia is a significant complication following thoracic and thoracoabdominal aortic aneurysm repair.
- Despite surgical advancements, preventing paraplegia remains a challenge.
Purpose of the Study:
- To identify risk factors for spinal cord ischemia.
- To review interventions for preventing and treating spinal cord ischemia.
- To reduce paraplegia, a severe complication of aortic aneurysm repair.
Main Methods:
- Review of risk factors including aneurysm extent, surgical approach, and perioperative hypotension.
- Evaluation of treatment strategies: augmenting spinal cord perfusion, cerebrospinal fluid drainage, and segmental artery reattachment.
- Emphasis on early detection via neurophysiologic monitoring and neurological examination.
Main Results:
- Aneurysm extent, open repair, prior aortic operations, and hypotension are key risk factors.
- Strategies like increased arterial pressure, CSF drainage, and artery reattachment improve perfusion.
- Early detection is crucial for timely intervention.
Conclusions:
- Permanent paraplegia can be prevented through early detection and prompt treatment of spinal cord ischemia.
- Interventions are justified by the high mortality and morbidity associated with paraplegia.
- Proactive management of spinal cord ischemia is essential in high-risk patients undergoing aortic repair.
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