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Updated: Jun 18, 2026

Full-Endoscopic Surgery for Hypothalamic Hamartoma Resection
Published on: April 12, 2024
Severe hyponatremia occurring after surgical stress in a patient with mitochondrial disease
Nobuko Sasano1, Tetsuya Tamura, Takafumi Azami
1Department of Anesthesia, Inabe General Hospital, Inabe, Mie, Japan.
Abstract:
A 53-year-old man with mitochondrial disease underwent gastrectomy because of gastric cancer. Three days after the surgery, he developed severe hyponatremia (Na, 106 mmol l(-1)) together with hypovolemic shock and lactic acidosis. Despite the hyponatremia, his urine sodium concentration was high, suggesting renal salt wasting. Although mitochondrial diseases are not common and hyponatremia in patients with these diseases is not well known, clinicians should pay close attention to serum sodium levels and maintain them properly.
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