Design of a well-absorbed renin inhibitor

Modeling improvements in digestible amino acids by a consensus bacterial 6-phytase variant in grower pigs.

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True metabolizable energy, standardized amino acid digestibility, phosphorus digestibility, and phosphorus bioavailability of fermented soybean meal and fermented full-fat soybeans fed to chickens.

Poultry science·2025

Host traits and temperature predict biogeographical variation in seagrass disease prevalence.

Proceedings. Biological sciences·2025

True metabolizable energy, standardized amino acid digestibility, and digestibility of phosphorus in soybean expellers produced from conventional or high-oil varieties of soybeans fed to chickens.

Poultry science·2024

Review: Aspects of digestibility and requirements for minerals and vitamin D by growing pigs and sows.

Animal : an international journal of animal bioscience·2024

Nutrient digestibility and endogenous protein losses in the foregut and small intestine of weaned dairy calves fed calf starters with conventional or enzyme-treated soybean meal.

Journal of dairy science·2021

Discovery of Monoterpenoid Indole Alkaloids Targeting CCN1 to Suppress Autophagy for the Treatment of Hypoxic Kidney Injury.

Journal of medicinal chemistry·2026

Selective Macrocyclic WEE1 Kinase Inhibitors with Strong Efficacy against Patient-Derived Colorectal Cancer Organoids.

Journal of medicinal chemistry·2026

Neutral Backbone Modifications Enhance the Pharmacokinetics and Biodistribution of Antibody-Oligonucleotide Conjugates with High Drug-to-Antibody Ratios.

Journal of medicinal chemistry·2026

Discovery of TL10: A Soluble and Long-Acting MC4R Agonist with Tunable Lipidation for Sustained Pharmacological Activity.

Journal of medicinal chemistry·2026

Discovery, Synthesis, and Biological Evaluation of 1,3,4,5-Tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one Derivatives as Novel and Highly Selective PARP1 Inhibitors.

Journal of medicinal chemistry·2026

Discovery and Optimization of Novel Nonhydroxamate LpxC Inhibitors for the Treatment of Multidrug-Resistant Gram-Negative Infections.

Journal of medicinal chemistry·2026

Network-guided Evaluation of β-sitosterol in Inflammatory and Profibrotic Mesangial-Cell Models Relevant to Chronic Glomerulonephritis.

Journal of visualized experiments : JoVE·2026

DyAb: sequence-based antibody design and property prediction in a low-data regime.

mAbs·2026

A nicotinic-dopaminergic hybrid probe enhances D2-like autoreceptor-mediated inhibition of dopamine release.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie·2026

Chemical biology tools for the O-GlcNAc modification: Determining systems-level functions and druggability.

Current opinion in chemical biology·2026

Hybrid design reveals a dopamine D3R ligand with promising in vitro ADME properties.

Bioorganic chemistry·2026

The structure of the dopamine D3 receptor bound to cariprazine reveals principles for partial agonists with designed pharmacology.

Science advances·2026

Related Experiment Videos

Design of a well-absorbed renin inhibitor

Related Concept Videos

Modeling improvements in digestible amino acids by a consensus bacterial 6-phytase variant in grower pigs.

True metabolizable energy, standardized amino acid digestibility, phosphorus digestibility, and phosphorus bioavailability of fermented soybean meal and fermented full-fat soybeans fed to chickens.

Host traits and temperature predict biogeographical variation in seagrass disease prevalence.

True metabolizable energy, standardized amino acid digestibility, and digestibility of phosphorus in soybean expellers produced from conventional or high-oil varieties of soybeans fed to chickens.

Review: Aspects of digestibility and requirements for minerals and vitamin D by growing pigs and sows.

Nutrient digestibility and endogenous protein losses in the foregut and small intestine of weaned dairy calves fed calf starters with conventional or enzyme-treated soybean meal.

Discovery of Monoterpenoid Indole Alkaloids Targeting CCN1 to Suppress Autophagy for the Treatment of Hypoxic Kidney Injury.

Selective Macrocyclic WEE1 Kinase Inhibitors with Strong Efficacy against Patient-Derived Colorectal Cancer Organoids.

Neutral Backbone Modifications Enhance the Pharmacokinetics and Biodistribution of Antibody-Oligonucleotide Conjugates with High Drug-to-Antibody Ratios.

Discovery of TL10: A Soluble and Long-Acting MC4R Agonist with Tunable Lipidation for Sustained Pharmacological Activity.

Discovery, Synthesis, and Biological Evaluation of 1,3,4,5-Tetrahydro-6H-pyrano[4,3-c]isoquinolin-6-one Derivatives as Novel and Highly Selective PARP1 Inhibitors.

Discovery and Optimization of Novel Nonhydroxamate LpxC Inhibitors for the Treatment of Multidrug-Resistant Gram-Negative Infections.

Network-guided Evaluation of β-sitosterol in Inflammatory and Profibrotic Mesangial-Cell Models Relevant to Chronic Glomerulonephritis.

DyAb: sequence-based antibody design and property prediction in a low-data regime.

A nicotinic-dopaminergic hybrid probe enhances D2-like autoreceptor-mediated inhibition of dopamine release.

Chemical biology tools for the O-GlcNAc modification: Determining systems-level functions and druggability.

Hybrid design reveals a dopamine D3R ligand with promising in vitro ADME properties.

The structure of the dopamine D3 receptor bound to cariprazine reveals principles for partial agonists with designed pharmacology.

Related Experiment Videos

Design of a well-absorbed renin inhibitor

Related Concept Videos

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