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Related Experiment Video

Updated: Jun 18, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

[Sentinel node in gynaecological cancers. Our experience].

S Vidal-Sicart1, B Doménech, B Luján

  • 1Servicio de Medicina Nuclear, CDI, Hospital Clínic Barcelona, Barcelona, España. svidal@clini.ub.es

Revista Espanola De Medicina Nuclear
|November 20, 2009
PubMed
Summary

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Sentinel lymph node (SLN) biopsy is effective for vulvar and cervical cancers but requires further refinement for endometrial cancer. This technique aids in staging gynaecological malignancies.

Area of Science:

  • Oncology
  • Surgical Pathology
  • Nuclear Medicine

Background:

  • Sentinel lymph node (SLN) identification is standard for melanoma and breast cancer.
  • Its adoption in gynaecologic cancers is limited by a lack of extensive validation studies.

Purpose of the Study:

  • To assess the feasibility and outcomes of the SLN technique in gynaecologic malignancies at our institution.

Main Methods:

  • 155 patients with vulvar, cervical, and endometrial cancers were studied.
  • Lymphoscintigraphy with (99m)Tc-nanocolloid was performed pre-surgically.
  • Intraoperative SLN detection used a gammaprobe and blue dye; pathological analysis was conducted on all SLNs.

Main Results:

  • SLN identification rates were 97% for vulvar, 92% for cervical, and 64% for endometrial cancers.

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Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
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Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

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Last Updated: Jun 18, 2026

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy
05:52

Sentinel Lymph Node Mapping and Biopsy for Endometrial Cancer at Early Stage with Laparoscopy

Published on: August 19, 2021

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology
06:37

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

  • Metastases were detected in 24.2% (vulvar), 8.8% (cervical), and 4.5% (endometrial) of patients.
  • False negative rates were 5.5% (vulvar), 0% (cervical), and 2 cases (endometrial).

    • Conclusions:

    • Lymphoscintigraphy is a practical method for SLN identification in gynaecologic tumors.
    • The SLN biopsy shows promise for vulvar and cervical malignancies.
    • Further optimization is needed for endometrial cancer SLN identification.