Search research articles

ABOUT JoVE

Overview Leadership Blog JoVE Help Center

AUTHORS

Publishing Process Editorial Board Scope & Policies Peer Review FAQ Submit

LIBRARIANS

Testimonials Subscriptions Access Resources Library Advisory Board FAQ

RESEARCH

JoVE Journal Methods Collections JoVE Encyclopedia of Experiments Archive

EDUCATION

JoVE Core JoVE Business JoVE Science Education JoVE Lab Manual Faculty Resource Center Faculty Site

Terms & Conditions of Use

Search research articles

Related Experiment Video

Updated: Jun 18, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

[SPECT-CT in sentinel node detection in patients with melanoma].

J Mucientes Rasilla¹, J Cardona Arboniés, R Delgado Bolton

¹Servicio de Medicina Nuclear, Hospital Clínico San Carlos, Madrid, España. jorgemuci@vodafone.es

Revista Espanola De Medicina Nuclear

|November 20, 2009

Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by

Same author

Expression of somatostatin receptors in lesions different from neuroendocrine tumors.

Revista espanola de medicina nuclear e imagen molecular·2025

Same author

Evaluation of the prognostic value of the metabolic volumetric parameters calculated with <sup>18</sup>F-FDG PET/CT and its value added to the molecular characteristics in patients with diffuse large B-cell lymphoma.

Revista espanola de medicina nuclear e imagen molecular·2022

Same author

Evaluation of the prognostic value of different methods of calculating the tumour metabolic volume with <sup>18</sup>F-FDG PET/CT, in patients with diffuse large cell B-cell lymphoma.

Revista espanola de medicina nuclear e imagen molecular·2020

Same author

[Diagnosis of COVID-19 pneumonia in asymptomatic patients after an oncological PET/CT].

Revista espanola de medicina nuclear e imagen molecular·2020

Same author

Criteria of metabolic response to immunotherapy.

Revista espanola de medicina nuclear e imagen molecular·2019

Same author

Can positron emission tomography support the characterization of immune-mediated inner ear disease?

Revista espanola de medicina nuclear e imagen molecular·2018

SPECT-CT imaging improved sentinel lymph node detection in melanoma patients, identifying the node in 100% of cases. This technique offers clinically relevant findings, especially for melanoma on the trunk or head and neck.

Area of Science:

Oncology
Nuclear Medicine
Diagnostic Imaging

Background:

Prognosis of cutaneous melanoma is significantly impacted by lymph node metastasis.
Sentinel lymph node biopsy (SLNB) is an innovative oncological approach.
Accurate sentinel node identification is crucial for melanoma staging and treatment.

Purpose of the Study:

To evaluate the contribution of SPECT-CT imaging in locating sentinel nodes for melanoma patients.
To assess the added value of SPECT-CT compared to conventional imaging techniques.

Main Methods:

A study involving 18 melanoma patients (10 female, 8 male) aged 14-83.
Sentinel node search utilized dynamic scintigraphy, planar imaging, and SPECT-CT.
Data collected from March 2007 to October 2008 at San Carlos University Hospital.

More Related Videos

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

Related Experiment Videos

Last Updated: Jun 18, 2026

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

The Application of 1% Methylene Blue Dye As a Single Technique in Breast Cancer Sentinel Node Biopsy

Published on: June 1, 2019

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Multispectral Real-time Fluorescence Imaging for Intraoperative Detection of the Sentinel Lymph Node in Gynecologic Oncology

Published on: October 20, 2010

Main Results:

Conventional imaging located sentinel nodes in 88.88% (16/18) of patients.
SPECT-CT successfully identified sentinel nodes in 100% (18/18) of patients.
Clinically relevant findings were detected by SPECT-CT in 33.33% (6/18) of cases.

Conclusions:

SPECT-CT imaging provides crucial clinical information for sentinel node assessment in melanoma.
The technique is particularly valuable for melanoma cases on the trunk and head/neck regions.
SPECT-CT enhances the diagnostic accuracy of sentinel lymph node biopsy in melanoma management.