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Kupffer Cell Isolation for Nanoparticle Toxicity Testing
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Kupffer Cell Isolation for Nanoparticle Toxicity Testing

Published on: August 18, 2015

Selective inhibition of NF-kappaB in Kupffer cells: good, but not for everything

Fabio Marra1

  • 1Dipartimento di Medicina Interna, Viale Morgagni 85, I-50134 Florence, Italy. f.marra@dmi.unifi.it

Gut
|November 20, 2009
PubMed
Abstract

No abstract available in PubMed .

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NF-κB-dependent Signaling Pathway02:26

NF-κB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...
NF-kB-dependent Signaling Pathway02:26

NF-kB-dependent Signaling Pathway

The transcription factor NF-κB was discovered in 1986 in the lab of Nobel laureate Professor David Baltimore, for its interaction with the immunoglobulin light chain enhancer in B-cells. After more than three decades of study, it is now evident that NF-κB regulates the expression of over 100 genes. Most of these genes play an essential role in the innate and adaptive immune responses as well as the inflammatory responses of animals.
NF-κB-dependent Signaling Mechanism
The heterodimer of NF-κB...

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