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Updated: Jun 18, 2026

Roux-en-Y Gastric Bypass Operation in Rats
Published on: June 11, 2012
Relationship between quality of life and weight loss 1 year after gastric bypass
Jennifer Klingemann1, Zoltan Pataky, Ileana Iliescu
1Service of Therapeutic Education for Chronic Diseases, WHO Collaborating Centre, Department of Community Medicine and Primary Care, University Hospitals of Geneva, Geneva, Switzerland.
Background/Aims:
Improving health-related quality of life (HRQoL) along with decreasing obesity-related morbidity is one of the cornerstones of bariatric surgery. The aim of the study was to investigate how losing weight influences the HRQoL 1 year after gastric bypass and whether HRQoL prior to surgery predicts the amount of weight loss 1 year after gastric bypass.
Methods:
One hundred and thirty-nine obese women [median (range): age 45 years (20-71), BMI 44 (29-88)] admitted for gastric bypass were selected prospectively and completed the Nottingham Health Profile (NHP) quality of life questionnaire before and 1 year after surgery.
Results:
Weight loss 1 year after gastric bypass was significant [-37 kg (9-74), p < 0.001] and led to an improvement of quality of life [NHP total score before surgery 62 (39-76) and after surgery 20 (7-65), p < 0.001].
Conclusions:
HRQoL improves dramatically 1 year after gastric bypass. This HRQoL improvement is not influenced by the amount of weight loss, but rather by the BMI achieved at that time.
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