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Updated: Jun 18, 2026

Intratracheal Inoculation of Fischer 344 Rats with Francisella tularensis
Published on: September 30, 2017
Vaccines against tularemia
Eileen M Barry1, Leah E Cole, Araceli E Santiago
1University of Maryland School of Medicine, Center for Vaccine Development, Baltimore, MD, USA. ebarry@medicine.umaryland.edu
Abstract:
Francisella tularensis is a Category A select agent for which vaccine and countermeasure development are a priority. In the past eight years, renewed interest in this pathogen has led to the generation of an enormous amount of new data on both the pathogen itself and its interaction with host cells. This information has fostered the development of various vaccine candidates including acellular subunit, killed whole cell and live attenuated. This review summarizes the progress and promise of these various candidates.
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