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Updated: Jun 18, 2026

Assembly and Characterization of Polyelectrolyte Complex Micelles
Published on: March 2, 2020
Spectral study of interaction between poly [acrylamide-(2-methyl acryloxyethyl) dimethyl buthylammonium bromide] and
Gongwu Song1, Mao Peng, Qiujun Yan
1Ministry of Education Key Laboratory for the Synthesis and Application of Organic Function Molecules, Hubei University, Wuhan, People's Republic of China. Songgw2008@yahoo.com.cn
Abstract:
A polycation, poly[acrylamide-(2-methylacryloxyethyl) dimethyl buthylammonium bromide] [P (AM-DMB)], was synthesized. The interaction between P (AM-DMB) and DNA was studied by spectral methods. Resonance light scattering spectra, FTIR-spectra and UV-spectra were used to study the mechanisms of the interaction. The results indicate that the conformation of the DNA alters during the interaction because the microenvironment of DNA changes. The binding constant K between P (AM-DMB) and DNA is 8.0 × 10(3) L mol(-1) .
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