Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Types of Step-Growth Polymers: Polyesters01:20

Types of Step-Growth Polymers: Polyesters

The introduction of polyesters has brought major development to the textile industry. The wrinkle-free behavior of polyester blends has eliminated the need for starching and ironing clothes.
Polyesters are commonly prepared from terephthalic acid and ethylene glycol; the crude product is known as poly(ethylene terephthalate) or PET. However, polyesters are synthesized industrially by transesterification of dimethyl terephthalate with ethylene glycol at 150 °C. The two reactants and the polymer...
Bioplastics01:27

Bioplastics

Bioplastics derived from microbial processes present a sustainable alternative to conventional petroleum-based plastics. Among these, polyhydroxyalkanoates (PHAs), particularly polyhydroxybutyrates (PHBs), have emerged as prominent candidates due to their biodegradability and biocompatibility. These polymers are synthesized by a variety of bacteria, such as Cupriavidus necator and Pseudomonas putida, which naturally accumulate PHAs as intracellular carbon and energy reserves, especially under...
Site-Targeted Drug Delivery Systems: Polymeric Carriers01:24

Site-Targeted Drug Delivery Systems: Polymeric Carriers

Polymeric carriers enhance targeted drug delivery by increasing efficacy while minimizing off-target effects. These carriers comprise a biodegradable polymeric backbone integrated with functional elements that enable targeting, improve physicochemical properties, and regulate drug release.Targeting MechanismsThe targeting ability of polymeric carriers is mediated by a homing device, which is a molecular recognition component designed to selectively bind to specific tissues or cells. Monoclonal...
Phosphodiester Linkages01:01

Phosphodiester Linkages

Overview
Phosphodiester bond forms when a phosphoric acid molecule (H3PO4) links with two hydroxyl groups (–OH) of two other molecules, forming two ester bonds. Two water molecules are released in this process. The phosphodiester bond is commonly found in nucleic acids (DNA and RNA) and plays a critical role in their structure and function.
Phosphodiester Bonds Link Nucleotides Together
DNA and RNA are polynucleotides or long chains of nucleotides that are linked together. A nucleotide is...

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Anionic Nanoparticles Co-Loaded with Regorafenib/Paclitaxel for Macrophage-Mediated Chemoimmunotherapy against Colorectal Peritoneal Metastases.

Nano letters·2026
Same author

Albumin-bound alkylated resiquimod for enhanced cancer immunotherapy.

Journal of controlled release : official journal of the Controlled Release Society·2026
Same author

Injectable Trojan Horse Hydrogel Unleashing Penetrable and Immunostimulatory Nanomicelles for Postoperative Treatment of Glioblastoma.

ACS nano·2026
Same author

"AND" Logic-Gated Biomimetic Nanoparticles to Activate Macrophage Phagocytosis for Cancer Immunotherapy.

Nano letters·2026
Same author

ATP-fueled STING activation of manganese coordinated nanoagonist to boost antitumor immunity.

Bioactive materials·2026
Same author

Pharmacotranscriptomics-based discovery and hydrogel-mediated delivery of drug combinations for potentiated cancer immunotherapy.

Science bulletin·2026

Related Experiment Video

Updated: Jun 18, 2026

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Recent progress in polyphosphoesters: from controlled synthesis to biomedical applications.

Yu-Cai Wang1, You-Yong Yuan, Jin-Zhi Du

  • 1Department of Polymer Science and Engineering and CAS Key Laboratory of Soft Matter Chemistry, University of Science and Technology of China, Hefei, Anhui 230027, PR China.

Macromolecular Bioscience
|November 20, 2009
PubMed
Summary

Polyphosphoesters (PPEs) are versatile, biocompatible polymers with potential in biomaterials. This review covers their synthesis, degradation, and biomedical applications, highlighting their promise for advanced materials.

More Related Videos

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Related Experiment Videos

Last Updated: Jun 18, 2026

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation
15:33

Microwave-assisted Functionalization of Poly(ethylene glycol) and On-resin Peptides for Use in Chain Polymerizations and Hydrogel Formation

Published on: October 29, 2013

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications
09:22

Fabricating Superhydrophobic Polymeric Materials for Biomedical Applications

Published on: August 28, 2015

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold
09:37

Fabrication of a Bioactive, PCL-based "Self-fitting" Shape Memory Polymer Scaffold

Published on: October 23, 2015

Area of Science:

  • Polymer Chemistry
  • Materials Science
  • Biomaterials

Background:

  • Polyphosphoesters (PPEs) possess repeating phosphoester bonds, offering structural versatility and biocompatibility.
  • Their biodegradability via hydrolysis and enzymatic digestion under physiological conditions makes them attractive for biological applications.
  • PPEs share similarities with biomacromolecules like nucleic acids, enhancing their biological relevance.

Purpose of the Study:

  • To review the expanding scope of polyphosphoesters (PPEs) in materials science, with a focus on biomaterials.
  • To highlight controlled synthetic methods for novel and complex PPE structures, including block copolymers.
  • To discuss degradation mechanisms, thermoresponsive properties, and biomedical applications of PPEs.

Main Methods:

  • Focus on controlled polymerization techniques for synthesizing PPEs.
  • Analysis of hydrolytic and enzymatic degradation pathways.
  • Investigation of thermoresponsive behavior and exploration of biomedical applications.

Main Results:

  • Controlled synthesis provides access to complex PPE architectures, particularly block copolymers.
  • PPEs exhibit tunable degradation profiles under physiological conditions.
  • Demonstrated potential for various biomedical applications.

Conclusions:

  • Polyphosphoesters are a promising class of materials for biomedical applications due to their unique properties.
  • Advances in controlled synthesis enable the design of sophisticated PPE-based materials.
  • Further research into PPEs will likely expand their utility in advanced biomaterials and therapeutics.