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Updated: Jun 18, 2026

Left Atrial Stenosis Induced Pulmonary Venous Arterialization and Group 2 Pulmonary Hypertension in Rat
Published on: November 18, 2018
Total anomalous pulmonary venous drainage to coronary sinus combined with left-sided obstructive lesions: a
Ghassan Hamdan Al-Naami1, Abdulrahman Abdulaziz Al-Mesned
1Pediatric Cardiology Department, Prince Sultan Cardiac Center-Qassim, Maternity and Children's Hospital of Buraidah, Qassim, Saudi Arabia. ghassanaami@hotmail.com
Insights
This study reports a rare heart defect combining abnormal pulmonary venous drainage and left-sided obstructive lesions. This unique cardiac malformation offers new insights into heart development and potential embryological disruptions.
Area of Science:
- Cardiology
- Developmental Biology
- Medical Case Reports
Background:
- Congenital heart disease encompasses a spectrum of structural abnormalities.
- Complex cardiac malformations often arise from disruptions during embryonic development.
- Understanding rare presentations is crucial for advancing pediatric cardiology.
Observation:
- A unique case of congenital heart disease is presented.
- The lesion features a combination of anomalous pulmonary venous connection and left-sided obstructive lesions.
- This specific combination has not been previously documented in medical literature.
Findings:
- Detailed description of a rare cardiac lesion combining abnormal pulmonary venous drainage and left-sided obstructive lesions.
- This case represents a novel finding in the field of congenital cardiac malformations.
- Literature review confirms the unprecedented nature of this combined lesion.
Implications:
- This case challenges current understanding of cardiac embryology and the timing of developmental events.
- It prompts further investigation into the etiology of complex heart malformations.
- Highlights the importance of reporting rare cardiac anomalies for advancing medical knowledge.
Abstract:
We present a very rare cardiac lesion where we found a combination of abnormal pulmonary venous drainage and left-sided obstructive lesions. This case gives new insight into the complex malformation of the heart, raising questions about cardiac embryology and timing of interfering events. Here we describe the lesion for the first time and review the related literature. To the best of our knowledge, this combination has never been reported.
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