The association between alcohol consumption and morbidity and mortality in patients undergoing coronary artery bypass

Ankit Maheshwari1, Jarrod E Dalton, Jean-Pierre Yared

  • 1Department of Outcomes Research, Cleveland Clinic Foundation, Cleveland, OH 44195, USA. mahesha@ccf.org

Insights

Moderate alcohol consumption (3+ drinks/week) did not improve postoperative outcomes in patients undergoing coronary artery bypass graft (CABG) surgery. This study found no significant association between regular alcohol intake and surgical complications or hospital stay.

Area of Science:

  • Cardiovascular Surgery
  • Alcohol Consumption Research
  • Perioperative Medicine

Background:

  • Moderate alcohol consumption is linked to reduced cardiovascular events in population studies.
  • Its impact on perioperative outcomes, particularly after coronary artery bypass graft (CABG) surgery, remains unclear.

Purpose of the Study:

  • To investigate the hypothesis that consuming 3 or more alcoholic drinks per week improves postoperative outcomes in patients undergoing CABG surgery.

Main Methods:

  • A propensity-matched retrospective cohort study analyzed data from 13,065 patients undergoing elective CABG surgery.
  • Patients were matched based on propensity scores to compare alcohol users with infrequent/nonusers.
  • Outcomes assessed included a composite of major morbidities and mortality, and hospital length of stay.

Main Results:

  • Patients consuming at least 3 drinks per week showed similar odds of the composite outcome compared to infrequent or nonusers (adjusted OR, 1.13; P=0.14).
  • Hospital length of stay was also not significantly related to alcohol consumption (adjusted HR, 1.03; P=0.28).

Conclusions:

  • Alcohol consumption of 3 or more drinks per week was not associated with a reduced risk of postoperative complications in CABG patients.
  • The study did not differentiate alcohol abusers, and findings may not apply to this group.
Abstract

Related Concept Videos

Coronary Artery Disease IV: Preventive Measures01:26

Coronary Artery Disease IV: Preventive Measures

Effective preventive measures for coronary artery disease (CAD) focus on controlling modifiable risk factors, including cholesterol abnormalities and lifestyle changes.Cholesterol ManagementFirst, the Mediterranean diet and the American Heart Association advocate for maintaining low-density lipoprotein (LDL) cholesterol levels below 100 mg/dL, with a more stringent recommendation of below 70 mg/dL for individuals at high risk. LDL cholesterol, often termed "bad cholesterol," can lead to the...
Peripheral Artery Disease V: Postoperative Nursing Management01:23

Peripheral Artery Disease V: Postoperative Nursing Management

During the postoperative period, it is crucial to focus on maintaining circulation, identifying and managing potential complications, and planning for discharge.Nursing AssessmentVital signs monitoring: Regularly monitor vital signs, including blood pressure, heart rate, respiratory rate, and temperature, to detect early signs of complications such as bleeding and infection.Circulation assessment: Monitor pulses, perform Doppler assessments, and check capillary refill, color, temperature, and...
Coronary Artery Disease I: Introduction01:30

Coronary Artery Disease I: Introduction

Coronary Artery Disease (CAD): An Overview with Scientific InsightsCoronary Artery Disease (CAD), often referred to as C-A-D, is a prevalent blood vessel disorder classified under the broader category of atherosclerosis. Atherosclerosis is a pathological process characterized by the hardening and narrowing of arteries due to the accumulation of atherosclerotic plaques. These plaques are composed of cholesterol, fatty substances, inflammatory cells, calcium, and fibrin, reducing blood flow to...
Coronary Artery Disease II: Pathophysiology01:26

Coronary Artery Disease II: Pathophysiology

Coronary Artery Disease (CAD) originates from a series of events that impair the function of coronary arteries, the blood vessels responsible for delivering oxygen-rich blood to the heart muscle. The pathophysiology of CAD is closely linked to atherosclerosis, a chronic inflammatory and lipid-driven condition affecting the vascular endothelium.1. Endothelial DamageThe process begins with damage to the vascular endothelium, which serves as a protective barrier between the blood and the vessel...
Hypothesis Test for Test of Independence01:16

Hypothesis Test for Test of Independence

The test of independence is a chi-square-based test used to determine whether two variables or factors are independent or dependent. This hypothesis test is used to examine the independence of the variables. One can construct two qualitative survey questions or experiments based on the variables in a contingency table. The goal is to see if the two variables are unrelated (independent) or related (dependent). The null and alternative hypotheses for this test are:
H0: The two variables (factors)...
Coronary Artery Disease V: Interprofessional Care01:27

Coronary Artery Disease V: Interprofessional Care

Interprofessional care for coronary artery disease includes pharmacological therapy and revascularization procedures.Pharmacological therapy for Coronary Artery Disease (CAD) aims to manage symptoms, prevent complications, and improve patient outcomes through various classes of medications:Antiplatelet Agents:Aspirin and Clopidogrel: These medications inhibit platelet aggregation, preventing blood clots, which is crucial for avoiding heart attacks and strokes. Doctors often prescribe these...