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Synthesis of some new S-triazine based chalcones and their derivatives as potent antimicrobial agents

Anjani Solankee1, Kishor Kapadia, Ana Cirić

  • 1Department of Chemistry, B.K.M.Science College, Valsad 396001, India. dranjani_solankee@yahoo.com

European Journal of Medicinal Chemistry
|November 21, 2009
PubMed

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The reaction of weakly electrophilic aryldiazonium (also called arenediazonium) salts with highly activated aromatic compounds leads to the formation of products with an —N=N— link, called an azo linkage. This reaction, presented in Figure 1, is known as diazo coupling and occurs without the loss of the nitrogen atoms of the aryldiazonium salt. Highly activated aromatic compounds such as phenols or arylamines favor the diazo coupling reaction. The coupling generally occurs at the para position.
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