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Updated: Jun 18, 2026

Modifying Levels of Maternal Dietary Folic Acid or Choline to Study the Impact of Deficiencies on Offspring Health Outcomes
Published on: June 28, 2024
Relationship between plasma folate and homocysteine concentrations in alcoholics according to liver enzyme activity
Bogdan Cylwik1, Lech Chrostek, Marta Daniluk
1Department of Biochemical Diagnostics, Medical University, Bialystok, Poland. cylwikb@umwb.edu.pl
Abstract:
The aim of this study was to evaluate the relationship between folate and homocysteine levels in alcoholics taking into consideration the liver enzyme activity as sensitive markers of hepatocellular injury. Folate and homocysteine concentrations did not differ between alcoholics classified according to the liver enzyme activity. The association between folate and homocysteine levels exists in the alcoholics with normal liver enzyme activity and in the controls. Therefore, we concluded that before the liver hepatocellular injury due to alcohol abuse, the correlation between folate and homocysteine concentrations in alcoholics exists as in the healthy controls. In the presence of hepatocellular injury, the association disappears.
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