[Outcome of percutaneous coronary intervention of graft occlusion post coronary artery bypass graft]

Area of Science:

• Cardiology
• Interventional Cardiology
• Vascular Surgery

Background:

• Coronary artery bypass grafting (CABG) is a common procedure for coronary artery disease.
• Graft occlusion is a significant complication following CABG, leading to angina and reduced cardiac function.
• Saphenous vein grafts are particularly prone to occlusion compared to arterial grafts.

Purpose of the Study:

• To assess the feasibility and efficacy of percutaneous coronary intervention (PCI) in treating bypass graft occlusion after CABG.
• To evaluate the procedural success, safety, and long-term outcomes of PCI in this patient population.

Main Methods:

• Retrospective analysis of 135 post-CABG patients with symptomatic graft occlusion.
• Angiographic assessment of 318 grafts, identifying occluded left internal mammary artery (LIMA) and saphenous vein grafts.
• Percutaneous coronary intervention (PCI) performed on 158 target lesions, including chronic total occlusions, with drug-eluting stent (DES) implantation.

Main Results:

• High procedural success rate of 96.3% for PCI.
• Low lesion success rate of 96.8%.
• Favorable 12-month outcomes with a 5.6% angiographic restenosis rate, 5.4% major adverse cardiac events, and 6.2% target vessel revascularization.

Conclusions:

• Percutaneous coronary intervention (PCI) is a safe and feasible option for managing graft occlusion post-coronary artery bypass grafting (CABG).
• PCI demonstrates high procedural success and favorable long-term clinical and angiographic results in this setting.
• The study supports PCI as an effective revascularization strategy for failed bypass grafts.