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Updated: Jun 18, 2026

The Synthesis, Characterization and Reactivity of a Series of Ruthenium N-triphosPh Complexes
Published on: April 10, 2015
Photochemical stereospecific hydrogenation of a Ru complex with an NAD(+)/NADH-type ligand
Takashi Fukushima1, Etsuko Fujita, James T Muckerman
1Institute for Molecular Science (IMS), 5-1 Higashiyama, Myodaiji, Okazaki, Aichi 444-8787, Japan.
Abstract:
A polypyridylruthenium complex with an NAD(+)/NADH model ligand, [Ru(bpy)(2)(pbn)](2+) [bpy = 2,2'-bipyridine; pbn = 2-(2-pyridyl)benzo[b]-1,5-naphthyridine] in a D(2)O/CH(3)CN/triethylamine solution, undergoes stereospecific hydrogenation to give Delta-(S)- and Lambda-(R)-[Ru(bpy)(2)(pbnDD)](2+) [pbnDD = 5,10-dideutero-2-(2-pyridyl)benzo[b]-1,5-naphthyridine] upon visible-light irradiation. This result clearly indicates the pathway via the pi-stacked dimer of the deuterated one-electron-reduced species. The reduction of [Ru(bpy)(2)(pbn)](2+) with Na(2)S(2)O(4) in D(2)O did not afford any stereospecific products. Furthermore, the more sterically crowded Ru complex, [Ru(dmb)(2)(pbn)](2+) (dmb = 6,6'-dimethyl-2,2'-bipyridine), did not produce the corresponding pbnDD species upon irradiation.
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