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NOX activity is increased in mild cognitive impairment.

Annadora J Bruce-Keller1, Sunita Gupta, Taryn E Parrino

  • 1Pennington Biomedical Research Center, Louisiana State University System, Baton Rouge, Louisiana 70808, USA. annadora.bruce-keller@pbrc.edu

Antioxidants & Redox Signaling
|November 26, 2009
PubMed
Summary

NADPH oxidase (NOX) activity increases in the temporal lobe during mild cognitive impairment, suggesting a role in early Alzheimer's disease pathogenesis. This NOX upregulation in neurons may contribute to disease development.

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