Secretory meningiomas of the orbit

Isaac O Karikari1, Nasreen A Syed, Thomas J Cummings

  • 1Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina 27710, USA.

Insights

Secretory meningiomas are rare, well-differentiated tumors. This study reports two orbital cases, highlighting their rarity in this location and reviewing existing literature.

Area of Science:

  • Neuropathology
  • Ophthalmology
  • Oncology

Background:

  • Meningiomas are diverse tumors with over 15 subtypes.
  • Tumors are classified as well-differentiated, atypical, or malignant.
  • Secretory meningiomas represent a rare, well-differentiated subtype.

Observation:

  • Orbital involvement by secretory meningiomas is exceptionally uncommon.
  • Two distinct cases of secretory meningiomas affecting the orbit are presented.
  • A comprehensive review of the current scientific literature was conducted.

Findings:

  • The presented cases contribute to the limited understanding of orbital secretory meningiomas.
  • Literature review confirms the rarity of this specific tumor location.
  • Analysis of case details and literature provides insights into clinical presentation and management.

Implications:

  • These findings underscore the need for increased awareness of rare meningioma subtypes in orbital diagnostics.
  • Further research is warranted to elucidate the specific characteristics and behavior of orbital secretory meningiomas.
  • Improved diagnostic and therapeutic strategies may arise from continued investigation into these rare tumors.

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