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Published on: January 17, 2018
Secretory meningiomas of the orbit
Isaac O Karikari1, Nasreen A Syed, Thomas J Cummings
1Division of Neurosurgery, Duke University Medical Center, Durham, North Carolina 27710, USA.
Abstract:
Meningiomas are histologically heterogeneous tumors with at least 15 different subtypes. They can be subdivided into well-differentiated, atypical, and anaplastic or malignant categories. The secretory meningioma is a well-differentiated variant, is relatively rare. Orbital involvement of secretory meningiomas is rarity. We report two cases of secretory meningiomas of orbit and review of current literature.
Insights
Secretory meningiomas are rare, well-differentiated tumors. This study reports two orbital cases, highlighting their rarity in this location and reviewing existing literature.
Area of Science:
- Neuropathology
- Ophthalmology
- Oncology
Background:
- Meningiomas are diverse tumors with over 15 subtypes.
- Tumors are classified as well-differentiated, atypical, or malignant.
- Secretory meningiomas represent a rare, well-differentiated subtype.
Observation:
- Orbital involvement by secretory meningiomas is exceptionally uncommon.
- Two distinct cases of secretory meningiomas affecting the orbit are presented.
- A comprehensive review of the current scientific literature was conducted.
Findings:
- The presented cases contribute to the limited understanding of orbital secretory meningiomas.
- Literature review confirms the rarity of this specific tumor location.
- Analysis of case details and literature provides insights into clinical presentation and management.
Implications:
- These findings underscore the need for increased awareness of rare meningioma subtypes in orbital diagnostics.
- Further research is warranted to elucidate the specific characteristics and behavior of orbital secretory meningiomas.
- Improved diagnostic and therapeutic strategies may arise from continued investigation into these rare tumors.
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